A novel diagnostic scoring system for pediatric appendicitis based on age and sex- adjusted hematological parameters

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dc.contributor.authorAydogdu, Bahattin
dc.contributor.authorAzizoglu, Mustafa
dc.contributor.authorArslan, Serkan
dc.contributor.authorAydogdu, Gulay
dc.contributor.authorBasuguy, Erol
dc.contributor.authorSalik, Fikret
dc.contributor.authorOkten, Mustafa
dc.date.accessioned2024-04-24T17:20:21Z
dc.date.available2024-04-24T17:20:21Z
dc.date.issued2023
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Acute appendicitis diagnosis can sometimes be a real challenge in pediatric patients. Objective: To establish the importance of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and other hematological parameters adjusted for age and sex in the prediction of acute appendicitis, as well as to describe a new scoring system. Material and methods: Medical records of 946 children hospitalized for acute appendicitis were retrospectively analyzed. A scoring system based on NLR, PLR, lymphocyte/monocyte ratio (LMR), and C-reactive protein (CRP) adjusted for age and sex was developed. Results: Patients were divided into group I, with negative examination, and group II, with acute appendiand PCR were higher in group II. The scores ranged from 0 to 8 points; 4.5 was determined to be the best cut-off point for acute appendicitis with the highest area under the curve (0.96), sensitivity (94%), specificity (86%), positive predictive value (97.5%), negative predictive value (65%), accuracy (92.6%) and misclassification rate (7.4%). Conclusion: The proposed scoring system, calculated based on patient age and gender, can be used for unnecessary surgeries to be avoided.en_US
dc.identifier.doi10.24875/GMM.M22000750
dc.identifier.endpage112en_US
dc.identifier.issn0016-3813
dc.identifier.issue2en_US
dc.identifier.startpage106en_US
dc.identifier.urihttps://doi.org/10.24875/GMM.M22000750
dc.identifier.urihttps://hdl.handle.net/11468/18974
dc.identifier.volume159en_US
dc.identifier.wosWOS:000962063000005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherAcad Nacional Medicina Mexicoen_US
dc.relation.ispartofGaceta Medica De Mexico
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPediatric Appendicitisen_US
dc.subjectAdjusted Neutrophil-Lymphocyte Ratioen_US
dc.subjectNovel Scoring Systemen_US
dc.titleA novel diagnostic scoring system for pediatric appendicitis based on age and sex- adjusted hematological parametersen_US
dc.titleA novel diagnostic scoring system for pediatric appendicitis based on age and sex- adjusted hematological parameters
dc.typeArticleen_US

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