A novel diagnostic scoring system for pediatric appendicitis based on age and sex- adjusted hematological parameters
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Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Acad Nacional Medicina Mexico
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Acute appendicitis diagnosis can sometimes be a real challenge in pediatric patients. Objective: To establish the importance of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and other hematological parameters adjusted for age and sex in the prediction of acute appendicitis, as well as to describe a new scoring system. Material and methods: Medical records of 946 children hospitalized for acute appendicitis were retrospectively analyzed. A scoring system based on NLR, PLR, lymphocyte/monocyte ratio (LMR), and C-reactive protein (CRP) adjusted for age and sex was developed. Results: Patients were divided into group I, with negative examination, and group II, with acute appendiand PCR were higher in group II. The scores ranged from 0 to 8 points; 4.5 was determined to be the best cut-off point for acute appendicitis with the highest area under the curve (0.96), sensitivity (94%), specificity (86%), positive predictive value (97.5%), negative predictive value (65%), accuracy (92.6%) and misclassification rate (7.4%). Conclusion: The proposed scoring system, calculated based on patient age and gender, can be used for unnecessary surgeries to be avoided.
Açıklama
Anahtar Kelimeler
Pediatric Appendicitis, Adjusted Neutrophil-Lymphocyte Ratio, Novel Scoring System
Kaynak
Gaceta Medica De Mexico
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
159
Sayı
2
