Is isolated autoantibody seropositivity a risk factor in the development of diabetic nephropathy in type 1 diabetic children?

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dc.authorid0000-0001-7724-9160en_US
dc.authorid0000-0003-0790-323Xen_US
dc.authorid0000-0002-5859-4177en_US
dc.authorid0000-0002-7046-8907en_US
dc.authorid0000-0002-9809-0977en_US
dc.authorid0000-0001-6177-2635en_US
dc.authorid0000-0002-3203-741Xen_US
dc.contributor.authorTaktak, Aysel
dc.contributor.authorKara, Mehtap Akbalık
dc.contributor.authorÇiçek, Neslihan
dc.contributor.authorAlparslan, Caner
dc.contributor.authorÜnal, Edip
dc.contributor.authorAğın, Mehmet
dc.contributor.authorÖzbek, Mehmet Nuri
dc.date.accessioned2023-08-03T06:05:04Z
dc.date.available2023-08-03T06:05:04Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: Diabetic nephropathy is one of the most important complications in diabetes mellitus. We aimed to examine the influence of organ-specific antibody seropositivity in diabetic nephropathy. Methods: Patients with type 1 diabetes and no evidence of celiac disease, thyroid dysfunction, and other kidney diseases and with an annual average HbA1c level <10%, body mass index <25 kg/m2 , and normal blood pressure were enrolled. Results: Eighty patients (39 boys and 41 girls) were evaluated. Twenty patients with moderately increased albuminuria (diabetic nephropathy group) and 60 patients without albuminuria (control group) showed no statistical difference in age, gender, diabetes duration, age at diagnosis, kidney function tests, and mean blood pressure measurements. Compared to control group, the mean anti-thyroglobulin level and anti-thyroxin peroxidase level were statistically higher in the diabetic nephropathy group, P = .004 and P = .045, respectively. However, the thyroid function tests were normal in either group. Conclusion: Determination of the impact of autoantibody seropositivity on the risk of diabetic nephropathy in type 1 dia betic children could be a non-traditional marker in the risk assessment of diabetic nephropathy.en_US
dc.identifier.citationTaktak, A., Kara, M. A., Çiçek, N., Alparslan, C., Ünal, E., Ağın, M. ve diğerleri. (2023). Is isolated autoantibody seropositivity a risk factor in the development of diabetic nephropathy in type 1 diabetic children?. Turkish Journal of Nephrology, 32(3), 249-254.en_US
dc.identifier.doi10.5152/turkjnephrol.2023.2289378
dc.identifier.endpage254en_US
dc.identifier.issn2667-4440
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85166949362
dc.identifier.scopusqualityQ4
dc.identifier.startpage249en_US
dc.identifier.trdizinid1188763
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1188763
dc.identifier.urihttps://hdl.handle.net/11468/12409
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1188763
dc.identifier.volume32en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorÜnal, Edip
dc.language.isoenen_US
dc.publisherTürk Nefroloji Derneğien_US
dc.relation.ispartofTurkish Journal of Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutoimmune diseasesen_US
dc.subjectChildrenen_US
dc.subjectNephropathyen_US
dc.subjectType 1 diabetes mellitusen_US
dc.titleIs isolated autoantibody seropositivity a risk factor in the development of diabetic nephropathy in type 1 diabetic children?en_US
dc.titleIs isolated autoantibody seropositivity a risk factor in the development of diabetic nephropathy in type 1 diabetic children?
dc.typeArticleen_US

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