Biological activities and phytochemical investigation of some Sideritis species

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dc.authorid0000-0002-4674-7009en_US
dc.authorid0000-0002-3479-3999en_US
dc.authorid0000-0003-3994-6576en_US
dc.authorid0000-0002-4090-7227en_US
dc.contributor.authorEruygur, Nuraniye
dc.contributor.authorKırcı, Damla
dc.contributor.authorAyaz, Fatma
dc.contributor.authorBağcı, Yavuz
dc.contributor.authorDoğu, Süleyman
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.date.accessioned2025-02-17T11:07:15Z
dc.date.available2025-02-17T11:07:15Z
dc.date.issued2024en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractOne of the most generally used plants for herbal tea is Sideritis L. species (Lamiaceae) which is commonly grown in the Mediterranean region and represented by 46 species and 53 taxa in Türkiye. Sideritis species are widely used in Türkiye due to their antispasmodic, antirheumatic, anti-inflammatory, and diuretic activities. In the present research, the effects against oxidative stress, and enzyme activitiy, as well as chemical compositions of the water and methanol extracts of seven Sideritis species (S. bilgeriana P.H. Davis), S. brevidens P.H. Davis, S. cilicica Boiss. & Balansa, S. erythrantha Boiss. & Heldr., subsp. cedretorum P. H. Davis, S. hololeuca Boiss. & Heldr., S. libanotica Labill. subsp. linearis (Benth.) Bornm., and S. libanotica Labill. subsp. violascens P. H. Davis.). Its main objective was to assess the suppression of five enzymes, tyrosinase, α-glucosidase, α-amylase, acetylcholinesterase (AChE), and butyrylcholinesterase, for the water and methanol extracts of seven different Sideritis species. The extracts were also assessed for antioxidant effects using various spectrophotometric methods involving DPPH,ABTS·+, and iron chelating, as well as the determination of total phenol and flavonoid amounts. As for the phytochemical investigation on Sideritis species, the phenolic compounds of the extracts were determined by LC-MS/MS analysis. Because of the LC-MS/MS analysis, Hierarchical Cluster Analysis was performed on four major components: quinic acid, chlorogenic acid, fumaric acid, and acacetin in the present work. As a result, our research indicates that Sideritis species, particularly S. cilicica, S. erythrantha, and S. libanotica subsp. linearis, deserve to be examined afterwards for their active secondary metabolites, which are thought to be responsible for their potential biological activities. Furthermore, the composition of extracts of Sideritis species was statistically analysed using the principal component.en_US
dc.description.sponsorshipSelcuk University SUBAP-20401143en_US
dc.identifier.citationEruygur, N., Kırcı, D., Ayaz, F., Bağcı, Y., Doğu, S. ve Yılmaz, M. A. (2024). Biological activities and phytochemical investigation of some Sideritis species. Indian Journal of Traditional Knowledge, 23(10), 988-998.en_US
dc.identifier.endpage998en_US
dc.identifier.issn0972-5938
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-85208719595
dc.identifier.scopusqualityQ2
dc.identifier.startpage988en_US
dc.identifier.urihttps://or.niscpr.res.in/index.php/IJTK/issue/view/327
dc.identifier.urihttps://hdl.handle.net/11468/29464
dc.identifier.volume23en_US
dc.identifier.wosWOS:001340902200008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.language.isoenen_US
dc.publisherNational Institute of Science Communication and Policy Researchen_US
dc.relation.ispartofIndian Journal of Traditional Knowledge
dc.relation.isversionof10.56042/ijtk.v23i10.14489en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntioxidant activityen_US
dc.subjectEnzyme inhibitory effecten_US
dc.subjectLC-MS/MSen_US
dc.subjectPhenolic compoundsen_US
dc.subjectSideritisen_US
dc.titleBiological activities and phytochemical investigation of some Sideritis speciesen_US
dc.titleBiological activities and phytochemical investigation of some Sideritis species
dc.typeArticleen_US

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