Pregnancy Associated with Brucellosis and Acute Viral Hepatitis: Course and Outcome (Co-infections in Pregnancy)

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dc.contributor.authorGulsun, Serda
dc.contributor.authorDorman, Vedat
dc.contributor.authorAslan, Selda
dc.contributor.authorGul, Talip
dc.date.accessioned2024-04-24T17:37:48Z
dc.date.available2024-04-24T17:37:48Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: To assess the outcome and course of pregnancies complicated by Brucellosis (BCS) and acute viral hepatitis (AVH) infections Design: Prospective study Setting: Diyarbakir State Hospital, Turkey Subjects: Eighty-eight pregnant women admitted to Diyarbakir State Hospital, Turkey Intervension: Serum agglutination test (SAT), Coombs anti-Brucella test and / or blood culture system were used in the diagnosis of BCS. Enzyme-linked immunosorbent assays (ELISA) and polymerase chain reaction (PCR) was used in the diagnosis of viral hepatitis. Main Outcome Measures: The clinical course and delivery pattern of 32 healthy pregnant women was compared with that of 32 pregnant women who had BCS and 24 pregnant women who were concurrently infected with BCS and AVH. Results: There was no maternal mortality. Preterm delivery occurred in 18.75% of the 32 pregnant women with BCS and 37.5% of 24 pregnant women with BCS and AVH (p = 0.004). The incidence of low birth weight was also significant between the two groups (p < 0.0001). Antepartum hemorrhage might be a warning sign of the occurrence of complications in pregnant women with BCS and AVH (p < 0.001). An important observation from the present study is that maternal BCS and AVH (even concurrent) had no effect on the incidence of congenital malformations or stillbirths; it did increase the incidence of prematurity and low birth weight over that seen in the general delivery population. Conclusion: In spite of the high complication rates, BCS and AVH in pregnancy are well-tolerated diseases even when they occur together.en_US
dc.identifier.endpage117en_US
dc.identifier.issn0023-5776
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-79958720404
dc.identifier.scopusqualityQ4
dc.identifier.startpage113en_US
dc.identifier.urihttps://hdl.handle.net/11468/21190
dc.identifier.volume43en_US
dc.identifier.wosWOS:000291451800006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherKuwait Medical Assocen_US
dc.relation.ispartofKuwait Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Viral Hepatitisen_US
dc.subjectBrucellosisen_US
dc.subjectPregnancyen_US
dc.titlePregnancy Associated with Brucellosis and Acute Viral Hepatitis: Course and Outcome (Co-infections in Pregnancy)en_US
dc.titlePregnancy Associated with Brucellosis and Acute Viral Hepatitis: Course and Outcome (Co-infections in Pregnancy)
dc.typeArticleen_US

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