Serum Adropin Level in the Early Period of ST-Elevation Myocardial Infarction and Its Relationship With Cobalamin and Folic Acid

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dc.contributor.authorAdiyaman, Mehmet Sahin
dc.contributor.authorErkan, Revsa Evin Canpolat
dc.contributor.authorKaya, Ilyas
dc.contributor.authorAdiyaman, Ozlem Aba
dc.date.accessioned2024-04-24T17:28:26Z
dc.date.available2024-04-24T17:28:26Z
dc.date.issued2022
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Studies on biomarkers in the diagnosis of myocardial infarction are ongoing. Adropin is a biomarker that has been studied and has been shown to have different effects. This study aimed to examine the adropin level of patients with myocardial infarction within the first 24 hours, as well as its relationship with cobalamin and folic acid.Material and methods: The control group included 70 patients whose troponin values did not increase and no coronary lesions were detected. In the ST-elevation myocardial infarction (STEMI) group, 70 patients with ST elevation on ECG and coronary total thrombosis on coronary angiography were evaluated. Coronary lesion severity was measured using the SYNergy between percutaneous coronary intervention (PCI) with TAXUS and Cardiac Surgery (SYNTAX) score tool. Hemogram, troponin, adropin, c-reactive protein (CRP), cobalamin, folic acid, and other biochemical parameters were evaluated in all patients.Results: In the STEMI group, a significant increase was observed in the adropin level along with the troponin and CRP levels in the first 24 hours (p<0.001). Cobalamin and folic acid levels were low in the same group (p:0.016, p<0.001). While a strong negative correlation was observed between adropin and cobalamin, no correlation was found with other parameters.Conclusion: The study supports that adropin could be used as a cardiac biomarker in the early stages of STEMI patients. Another result is with low cobalamin and folic acid levels in patients with myocardial infarction which needs to be further explained with the strong negative correlation between adropin and cobalamin.en_US
dc.identifier.doi10.7759/cureus.32748
dc.identifier.issn2168-8184
dc.identifier.issue12en_US
dc.identifier.pmid36686140
dc.identifier.urihttps://doi.org/10.7759/cureus.32748
dc.identifier.urihttps://hdl.handle.net/11468/20437
dc.identifier.volume14en_US
dc.identifier.wosWOS:000905594300007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherCureus Incen_US
dc.relation.ispartofCureus Journal of Medical Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectStemien_US
dc.subjectCobalaminen_US
dc.subjectFolic Aciden_US
dc.subjectBiomarkeren_US
dc.subjectAdropinen_US
dc.titleSerum Adropin Level in the Early Period of ST-Elevation Myocardial Infarction and Its Relationship With Cobalamin and Folic Aciden_US
dc.titleSerum Adropin Level in the Early Period of ST-Elevation Myocardial Infarction and Its Relationship With Cobalamin and Folic Acid
dc.typeArticleen_US

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