Determination of anticholinesterase and antioxidant activities of methanol and water extracts of leaves and fruits of Chamaerops humilis L.

Basit Öğe Kaydı
dc.contributor.authorBouhafsoun, Aicha
dc.contributor.authorBoğa, Mehmet
dc.contributor.authorBoukeloua, Ahmed
dc.contributor.authorTemel, Hamdi
dc.contributor.authorKaid-Harche, Meriem
dc.date.accessioned2024-04-24T17:58:14Z
dc.date.available2024-04-24T17:58:14Z
dc.date.issued2019
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractThe present study was carried out to investigate the antioxidant activity of the water and methanol extracts of leaves and fruits extracts of Chamaerops humilis L. by using ABTS cation radicals and cupric reducing antioxidant capacity (CUPRAC). Anticholinesterase effect of the extracts was tested against both AChE and BChE using a microplate-reader assay based on the Ellman method. The methanol extracts of C. humilis leaves contained relatively higher content of flavonoids and total phenolics than those of fruits. All the extracts were found to have different levels of antioxidant activity in the systems tested. The leave extract showed the highest value of antioxidant activity, based on ABTS radical-scavenging activity, while the fruit water extract showed the highest value (0.53±0.50 µg/ mL) of cupric reducing antioxidant activity. Our data indicates that both methanol and water fruit extract were active for BChE inhibition (31.65 ± 0.37 and 30.19 ± 0.56%) respectively, whereas, all leave extracts did not show any activity against BChE. The present study demonstrated that the methanol and water extracts fractions of C. humilis have different responses with different antioxidant methods. Our results suggest that the C. humilis could be used as a source of antioxidant agents and may be beneficial in the AD treatment.en_US
dc.description.sponsorshipThis work is supported by High Teaching and Scientific Research Ministry www.mesrs.dz The authors are greatful to Dicle University Faculty of pharmacy for opening its laboratory facility.en_US
dc.identifier.citationBouhafsoun, A., Boğa, M., Boukeloua, A., Temel, H. ve Kaid-Harche, M. (2019). Determination of anticholinesterase and antioxidant activities of methanol and water extracts of leaves and fruits of Chamaerops humilis L.. Journal of Applied and Natural Science, 11(1), 144-148.
dc.identifier.doi10.31018/jans.v11i1.2001
dc.identifier.endpage148en_US
dc.identifier.issn0974-9411
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85140611323
dc.identifier.scopusqualityQ4
dc.identifier.startpage144en_US
dc.identifier.urihttps://doi.org/10.31018/jans.v11i1.2001
dc.identifier.urihttps://hdl.handle.net/11468/23746
dc.identifier.volume11en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherApplied and Natural Science Foundationen_US
dc.relation.ispartofJournal of Applied and Natural Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiological activityen_US
dc.subjectChamaerops Humilis Len_US
dc.subjectMethanol extracten_US
dc.subjectSecondary metabolitesen_US
dc.subjectWater extracten_US
dc.titleDetermination of anticholinesterase and antioxidant activities of methanol and water extracts of leaves and fruits of Chamaerops humilis L.en_US
dc.titleDetermination of anticholinesterase and antioxidant activities of methanol and water extracts of leaves and fruits of Chamaerops humilis L.
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
View of Determination of anticholinesterase and antioxidant activities of methanol and water extracts of leaves and fruits of Chamaerops humilis L_.pdf
Boyut:
863.33 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu