Determination of anticholinesterase and antioxidant activities of methanol and water extracts of leaves and fruits of Chamaerops humilis L.
Yükleniyor...
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Applied and Natural Science Foundation
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The present study was carried out to investigate the antioxidant activity of the water and methanol extracts of leaves and fruits extracts of Chamaerops humilis L. by using ABTS cation radicals and cupric reducing antioxidant capacity (CUPRAC). Anticholinesterase effect of the extracts was tested against both AChE and BChE using a microplate-reader assay based on the Ellman method. The methanol extracts of C. humilis leaves contained relatively higher content of flavonoids and total phenolics than those of fruits. All the extracts were found to have different levels of antioxidant activity in the systems tested. The leave extract showed the highest value of antioxidant activity, based on ABTS radical-scavenging activity, while the fruit water extract showed the highest value (0.53±0.50 µg/ mL) of cupric reducing antioxidant activity. Our data indicates that both methanol and water fruit extract were active for BChE inhibition (31.65 ± 0.37 and 30.19 ± 0.56%) respectively, whereas, all leave extracts did not show any activity against BChE. The present study demonstrated that the methanol and water extracts fractions of C. humilis have different responses with different antioxidant methods. Our results suggest that the C. humilis could be used as a source of antioxidant agents and may be beneficial in the AD treatment.
Açıklama
Anahtar Kelimeler
Biological activity, Chamaerops Humilis L, Methanol extract, Secondary metabolites, Water extract
Kaynak
Journal of Applied and Natural Science
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
11
Sayı
1
Künye
Bouhafsoun, A., Boğa, M., Boukeloua, A., Temel, H. ve Kaid-Harche, M. (2019). Determination of anticholinesterase and antioxidant activities of methanol and water extracts of leaves and fruits of Chamaerops humilis L.. Journal of Applied and Natural Science, 11(1), 144-148.
