Expression of the Homeobox Proteins Dlx-5 and TLX1 During the Development of Cat Testis

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dc.contributor.authorTopaloglu, Ugur
dc.contributor.authorAkbalik, Mehmet Erdem
dc.date.accessioned2024-04-24T17:33:56Z
dc.date.available2024-04-24T17:33:56Z
dc.date.issued2022
dc.departmentDicle Üniversitesien_US
dc.description.abstractRecent studies have shown that homeobox proteins play an important role in the formation and development of tissues and organs in the embryonic period. In our study, the distribution of Dlx-5 and TLX proteins, which are members of the homeobox family, in the testis, epididymis and ductus deferens ducts of some cat breeds were investigated. For this purpose, in the study, 18 testes younger than six months (immature) and older than one year (mature) were examined under a light microscope using an immunohistochemical method (indirect streptavidin-biotin complex). While it was determined that Dlx-5 and TLX1 proteins were expressed at varying levels in cells in immature and mature cat testicles, epithelial cells of ductus epididymis and ductus deferens, and smooth muscle cells of ductus deferens, no differences were observed between cat breeds. Dlx-5 immunoreactivity was more intense in the testes, epididymis and deferens ducts of immature and mature compared to TLX1. These results suggested that both proteins play important roles in the development of male feline genital organs and in the secretion and differentiation of cells, and also further observation of Dlx-5 expression suggested that this protein may be more effective than TLX1 in testicular development and physiological processes.en_US
dc.identifier.endpage626en_US
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85134717172
dc.identifier.scopusqualityQ3
dc.identifier.startpage619en_US
dc.identifier.urihttps://hdl.handle.net/11468/20895
dc.identifier.volume40en_US
dc.identifier.wosWOS:000830996700013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal of Morphology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCaten_US
dc.subjectDlx-5en_US
dc.subjectImmunohistochemistryen_US
dc.subjectTestisen_US
dc.subjectTlx1en_US
dc.titleExpression of the Homeobox Proteins Dlx-5 and TLX1 During the Development of Cat Testisen_US
dc.titleExpression of the Homeobox Proteins Dlx-5 and TLX1 During the Development of Cat Testis
dc.typeArticleen_US

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