Determination of Acetaminophen in Commercial Formulations Using Silver Nanostructured Aniline Modified Pencil Graphite Electrode

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dc.contributor.authorGuzel, Remziye
dc.contributor.authorEksi, Haslet
dc.contributor.authorDinc, Erdal
dc.contributor.authorSolak, Ali Osman
dc.date.accessioned2024-04-24T17:12:04Z
dc.date.available2024-04-24T17:12:04Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractA nanostructured silver-aniline modified pencil electrode obtained by applying experimental design and optimization was developed for the differential pulse stripping voltammetric quantification of acetaminophen in the pharmaceutical products, tablet and syrup. The electrode development process was performed by the modification of PGE with aniline using CV procedure and the reduction of silver nanoparticle on the polyaniline modified PGE. As a result, a new electrode system consisting of a nanostructured silver-polyaniline modified pencil graphite electrode (AgNS-PA-PGE) was obtained to reach a well-defined and higher peak current for the analysis of the related drug. The calibration curve was found linear in the range of 5 x 10(-8)-8 x 10(-7) M for acetaminophen. The validity and applicability of the proposed voltammetric method was tested by analyzing independent validation samples. It was observed that the proposed voltammetric approach for the real tablet and syrup samples gave successful analysis results. (C) 2013 The Electrochemical Society. All rights reserved.en_US
dc.description.sponsorshipAnkara University [10A3336001]en_US
dc.description.sponsorshipThis work was done within the Chemometric Laboratory of Faculty of Pharmacy and it was supported by the scientific research project No. 10A3336001 of Ankara University.en_US
dc.identifier.doi10.1149/2.102308jes
dc.identifier.endpageB124en_US
dc.identifier.issn0013-4651
dc.identifier.issn1945-7111
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-85016863666
dc.identifier.scopusqualityQ1
dc.identifier.startpageB119en_US
dc.identifier.urihttps://doi.org/10.1149/2.102308jes
dc.identifier.urihttps://hdl.handle.net/11468/17838
dc.identifier.volume160en_US
dc.identifier.wosWOS:000324810000052
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElectrochemical Soc Incen_US
dc.relation.ispartofJournal of The Electrochemical Society
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleDetermination of Acetaminophen in Commercial Formulations Using Silver Nanostructured Aniline Modified Pencil Graphite Electrodeen_US
dc.titleDetermination of Acetaminophen in Commercial Formulations Using Silver Nanostructured Aniline Modified Pencil Graphite Electrode
dc.typeArticleen_US

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