Seawater gel in allergic rhinitis: Entrapment effect and mucociliary clearance compared with saline

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dc.contributor.authorCingi, Cemal
dc.contributor.authorÜnlü, Halis H.
dc.contributor.authorSongu, Murat
dc.contributor.authorYalçın, Şinasi
dc.contributor.authorTopçu, İsmail
dc.contributor.authorÇaklı, Hamdi
dc.contributor.authorBal, Cengiz
dc.date.accessioned2024-04-24T17:56:33Z
dc.date.available2024-04-24T17:56:33Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: We performed a prospective study to investigate the the efficacy of seawater gel in reducing symptoms in patients with mild allergic rhinitis. We also aimed to investigate the impact of nasal irrigation on mucociliary clearance with seawater gel compared with saline in this patient group. Methods: The study was performed in 100 consecutive adult individuals with a history of allergic rhinitis that was not controlled by anti-allergic drugs. Patients were assigned to receive seawater gel nasal spray for 10 days. The efficacy of treatment was assessed by means of total nasal symptom score and clinical findings. Results: A statistically significant difference was found between scores of ‘nasal discharge, nasal obstruction, sneezing, nasal itching—before and after treatment (p < 0.001). Clinical findings evaluation revealed a statistically significant decrease in lower turbinate colour rating and turbinate congestion at the end of treatment (p< 0.001). Saccharin transit time decreased from baseline in the seawater trials by 12% compared with a 4% decrease for saline. The difference between the percent changes was statistically significant (t = 2.177; p < 0.05). Conclusions: The present study provides evidence that a four times daily regimen of seawater gel can be an adjunctive therapy in the patient with allergic rhinitis.en_US
dc.identifier.citationCingi, C., Ünlü, H. H., Songu, M., Yalçın, Ş., Topçu, İ., Çaklı, H. ve diğerleri. (2010). Seawater gel in allergic rhinitis: Entrapment effect and mucociliary clearance compared with saline. Therapeutic Advances in Respiratory Disease, 4(1), 13-18.
dc.identifier.doi10.1177/1753465809358190
dc.identifier.endpage18en_US
dc.identifier.issn1753-4658
dc.identifier.issue1en_US
dc.identifier.pmid20042452
dc.identifier.scopus2-s2.0-76349094473
dc.identifier.scopusqualityQ1
dc.identifier.startpage13en_US
dc.identifier.urihttps://doi.org/10.1177/1753465809358190
dc.identifier.urihttps://hdl.handle.net/11468/23566
dc.identifier.volume4en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofTherapeutic Advances in Respiratory Disease
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAllergenen_US
dc.subjectAllergic rhinitisen_US
dc.subjectEntrappingen_US
dc.subjectNasal lavageen_US
dc.subjectNasal rinsingen_US
dc.subjectSeawateren_US
dc.titleSeawater gel in allergic rhinitis: Entrapment effect and mucociliary clearance compared with salineen_US
dc.titleSeawater gel in allergic rhinitis: Entrapment effect and mucociliary clearance compared with saline
dc.typeArticleen_US

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