Immunohistochemical evaluation of iron accumulation in term placenta of preeclamptic patients

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dc.contributor.authorNasir, Yasemin
dc.contributor.authorNergiz, Yusuf
dc.contributor.authorAktas, Ayfer
dc.contributor.authorAkdeniz, Nurten
dc.date.accessioned2024-04-24T17:37:31Z
dc.date.available2024-04-24T17:37:31Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractPreeclampsia is a disease which involves hypertension and multisystem, it effects approximately 2 to 8% of all pregnancies and is a significant cause of maternal and newborn mortality and morbidity. It develops in the placenta and its pathogenesis is associated with placental abnormalities. Classical immunohistochemical studies on placenta have shown that there is a linear increase in iron storage in the placenta in the first half of a normal pregnancy, however, these stocks are decreased in normal 3rd trimester placenta. Iron accumulation in term placentas of preeclamptic and normal pregnancies were evaluated in this study. Ferritin immunostaining was observed to be more intense in preeclamptic group than in the control group, especially in Hofbauer cells, subtrophoblastic areas of stem villous, perivasculer stroma and villous stroma. Statistical analysis of the data was performed using SPSS software. Mann Whitney U test was used in the analysis and P values below 0.05 were statistically significant. In this study, iron accumulations in normotensif and preeclamptic placentas were compared.en_US
dc.identifier.endpage11279en_US
dc.identifier.issn1684-5315
dc.identifier.issue54en_US
dc.identifier.scopus2-s2.0-80053088568
dc.identifier.scopusqualityN/A
dc.identifier.startpage11273en_US
dc.identifier.urihttps://hdl.handle.net/11468/20984
dc.identifier.volume10en_US
dc.identifier.wosWOS:000299736000026
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.relation.ispartofAfrican Journal of Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPreeclampsiaen_US
dc.subjectPlacentaen_US
dc.subjectImmunohistochemistryen_US
dc.subjectIron Accumulationen_US
dc.titleImmunohistochemical evaluation of iron accumulation in term placenta of preeclamptic patientsen_US
dc.titleImmunohistochemical evaluation of iron accumulation in term placenta of preeclamptic patients
dc.typeArticleen_US

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