Sertraline-Induced Stuttering in an Adolescent with Autism Spectrum Disorder

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dc.authoridOzturk, Masum/0000-0002-9989-7051
dc.contributor.authorOzturk, Masum
dc.date.accessioned2025-02-22T14:08:35Z
dc.date.available2025-02-22T14:08:35Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractThere is also evidence that stuttering is caused by an adverse reaction to various medications. Antiepileptic drugs, antidepressants, antipsychotics, and methylphenidate have all been linked to drug-induced stuttering. The patient was 13 years old (male) and was diagnosed with autism spectrum disorder, attention deficit hyperactivity disorder, and mild mental retardation. The patient had language development and was able to form sentences of 4-5 words. Atomoxetine 50 mg/day and aripiprazole 15 mg/day treatment was used. Sertraline 50 mg/day treatment was initiated because of repeated questioning, order-symmetry compulsions and repetitive behaviors. Approximately one month after the initiation of sertraline treatment, the patient came for a follow-up visit and it was found that the compulsions of the patient had decreased, but one week after sertraline treatment, it was learned that the patient started to have word blocks, prolongation of words and repetitions during speech. No pathology was found in the examination, hemogram and biochemistry tests, brain MRI and EEG tests. After sertraline treatment was discontinued, the stuttering of the patient gradually decreased and improved within 2 weeks. Both serotonergic and dopaminergic effects of sertraline as well as autism spectrum disorder (white matter anomalies) are thought to contribute to sertraline-induced stuttering.en_US
dc.identifier.doi10.58600/eurjther2172
dc.identifier.issn2564-7784
dc.identifier.issn2564-7040
dc.identifier.issue3en_US
dc.identifier.trdizinid1249020en_US
dc.identifier.urihttps://doi.org/10.58600/eurjther2172
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1249020
dc.identifier.urihttps://hdl.handle.net/11468/29493
dc.identifier.volume30en_US
dc.identifier.wosWOS:001235756700001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorOzturk, Masum
dc.language.isoenen_US
dc.publisherPera Yayincilik Hizmetlerien_US
dc.relation.ispartofEuropean Journal of Therapeuticsen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectstutteringen_US
dc.subjectsertralineen_US
dc.subjectautismen_US
dc.subjectadolescenten_US
dc.subjectantidepressanten_US
dc.titleSertraline-Induced Stuttering in an Adolescent with Autism Spectrum Disorderen_US
dc.typeLetteren_US

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