Malignant ovarian germ cell tumors: Analysis of 32 cases

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dc.contributor.authorYilmaz F.
dc.contributor.authorGül T.
dc.contributor.authorUzunlar A.K.
dc.date.accessioned2024-04-24T18:43:53Z
dc.date.available2024-04-24T18:43:53Z
dc.date.issued2003
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: In this study, some clinicopathologic characteristics and the outcome of patients with malignant ovarian germ cell tumors (MOGCT) were evaluated. Materials and Methods. The clinical charts and pathologic reports of 32 patients with MOGCT treated at the Department of Obstetrics and Gynecology, and diagnosed at the Department of Pathology, Medical Faculty of Dicle University, Turkey from 1983 to 1999 were reviewed. Results: Thirteen patients (40.6%) had dysgerminoma, nine (28.1%) had immature teratoma (four grade 1, three grade 2, and two grade 3), eight (25%) had endodermal sinus tumor, and two (6.3%) patients had mixed germ cell tumors. Site of involvement was unilateral in 30 (19 on the right and 11 on the left) and bilateral in two. All patients underwent primary surgery and 26 patients combination chemotherapy. There seemed to be a relationship between pathologic findings and clinical outcome, and MOGCT histologic types may affect the prognosis. Conclusion: Dysgerminoma had a better prognosis than the nondysgerminomatous group (p < 0.05). This study provides additional data in confirmation of previous reports that management of MOGCT with fertility preservation is safe.en_US
dc.identifier.endpage573en_US
dc.identifier.issn0392-2936
dc.identifier.issue6en_US
dc.identifier.pmid14658607en_US
dc.identifier.scopus2-s2.0-0344013029en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage569en_US
dc.identifier.urihttps://hdl.handle.net/11468/24439
dc.identifier.volume24en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofEuropean Journal of Gynaecological Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChemotherapyen_US
dc.subjectFertilityen_US
dc.subjectMalignant Ovarian Germ Cell Tumorsen_US
dc.subjectTreatmenten_US
dc.titleMalignant ovarian germ cell tumors: Analysis of 32 casesen_US
dc.typeReview Articleen_US

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