Outcome of the respiratory syncytial virus related acute lower respiratory tract infection among hospitalized newborns: A prospective multicenter study

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dc.contributor.authorAlan, Serdar
dc.contributor.authorErdeve, Ömer
dc.contributor.authorÇakır, Ufuk
dc.contributor.authorAkduman, Hasan
dc.contributor.authorZenciroǧlu, Ayşegül
dc.contributor.authorAkçakuş, Mustafa
dc.contributor.authorTunç, Turan
dc.contributor.authorErtuǧrul, Sabahattin
dc.date.accessioned2024-04-24T17:58:14Z
dc.date.available2024-04-24T17:58:14Z
dc.date.issued2016
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractAim: To determine the incidence and outcomes of respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (ALRI) including morbidity, nosocomial infection and mortality among newborn infants who were admitted to the neonatal intensive care units (NICUs).Methods: A multicenter, prospective study was conducted in newborns who were hospitalized with community acquired or nosocomial RSV infection in 44 NICUs throughout Turkey. Newborns with ALRI were screened for RSV infection by Respi-Strip®-test. Main outcome measures were the incidence of RSV-associated admissions in the NICUs and morbidity, mortality and epidemics results related to these admissions.Findings: The incidence of RSV infection was 1.24% (n: 250) and RSV infection constituted 19.6% of all ALRI hospitalizations, 226 newborns (90.4%) had community-acquired whereas 24 (9.6%) patients had nosocomial RSV infection in the NICUs. Of the 250 newborns, 171 (68.4%) were full-term infants, 183 (73.2%) had a BW >2500 g. RSV-related mortality rate was 1.2%. Four NICUs reported seven outbreaks on different months, which could be eliminated by palivizumab prophylaxis in one NICU.Conclusion: RSV-associated ALRI both in preterm and term infants accounts an important percent of hospitalizations in the season, and may threat other high-risk patients in the NICU.en_US
dc.description.sponsorshipThis trial was supported by the Children Diseases Foundation, which is an independent organization funded by physicians from Ankara University School of Medicine, Department of Pediatrics.en_US
dc.identifier.citationAlan, S., Erdeve, Ö., Çakır, U., Akduman, H., Zenciroǧlu, A. Akçakuş, M. ve diğerleri. (2016). Outcome of the respiratory syncytial virus related acute lower respiratory tract infection among hospitalized newborns: A prospective multicenter study. Journal of Maternal-Fetal and Neonatal Medicine, 29(13), 2186-2193.
dc.identifier.doi10.3109/14767058.2015.1079614
dc.identifier.endpage2193en_US
dc.identifier.issn1476-7058
dc.identifier.issue13en_US
dc.identifier.pmid26365531
dc.identifier.scopus2-s2.0-84941242331
dc.identifier.scopusqualityQ1
dc.identifier.startpage2186en_US
dc.identifier.urihttps://doi.org/10.3109/14767058.2015.1079614
dc.identifier.urihttps://hdl.handle.net/11468/23748
dc.identifier.volume29en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltden_US
dc.relation.ispartofJournal of Maternal-Fetal and Neonatal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeonatal intensive care uniten_US
dc.subjectNewbornen_US
dc.subjectNosocomialen_US
dc.subjectOutbreaken_US
dc.subjectRespiratory syncytial virusen_US
dc.titleOutcome of the respiratory syncytial virus related acute lower respiratory tract infection among hospitalized newborns: A prospective multicenter studyen_US
dc.titleOutcome of the respiratory syncytial virus related acute lower respiratory tract infection among hospitalized newborns: A prospective multicenter study
dc.typeArticleen_US

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