Study of radiotherapy properties and antimicrobial activity of Glyconanoparticles (GNPs) generated from imidazolium salts

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dc.authorid0000-0003-3452-8551en_US
dc.authorid0000-0001-7354-3098en_US
dc.contributor.authorTelli, Fatma Çetin
dc.contributor.authorYavuz, Murat
dc.contributor.authorDenizaltı, Serpil
dc.contributor.authorSalman, Yeşim
dc.date.accessioned2023-10-05T12:22:12Z
dc.date.available2023-10-05T12:22:12Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Fen Fakültesi, Kimya Bölümüen_US
dc.description.abstractCarbohydrate-based imidazolium salts (IMSs) are structural patterns for the synthesis of pharmaceutically and biologically active substances. For this purpose, the chiral furanoside-based imidazolium salt conjugated with a cysteamine (Cyt) linker attached gold and silver nanoparticles were prepared in this study. The biological applications of the HeLa and A549 cell lines using MTT cell proliferation method were exhibited to determine the biological evaluation of NPs conjugated with sugar based imidazolium salt. The satisfactory results obtained demonstrated that the synthesized glyconanoconjugates were radiotherapeutic agents. Moreover, this modification type within a galactose derived imidazolium salt is the first work in bioapplications, especially in radiotherapy. The antimicrobial activity of IMSs and their nanoconjugates against test pathogens was also evaluated using the disc diffusion technique.en_US
dc.identifier.citationTelli, F. Ç., Yavuz, M., Denizaltı, S. ve Salman, Y. (2023). Study of radiotherapy properties and antimicrobial activity of Glyconanoparticles (GNPs) generated from imidazolium salts. ChemistrySelect, 8(13), 1-11.en_US
dc.identifier.doi10.1002/slct.202203810
dc.identifier.endpage11en_US
dc.identifier.issn2365-6549
dc.identifier.issue13en_US
dc.identifier.scopus2-s2.0-85152057129
dc.identifier.scopusqualityQ3
dc.identifier.startpage1en_US
dc.identifier.urihttps://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202203810
dc.identifier.urihttps://hdl.handle.net/11468/12750
dc.identifier.volume8en_US
dc.identifier.wosWOS:000962846900001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYavuz, Murat
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Inc.en_US
dc.relation.ispartofChemistrySelect
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntimicrobial activityen_US
dc.subjectGlyconanoconjugatesen_US
dc.subjectGlyconanoparticlesen_US
dc.subjectImidazolium saltsen_US
dc.subjectRadiosensitivityen_US
dc.titleStudy of radiotherapy properties and antimicrobial activity of Glyconanoparticles (GNPs) generated from imidazolium saltsen_US
dc.titleStudy of radiotherapy properties and antimicrobial activity of Glyconanoparticles (GNPs) generated from imidazolium salts
dc.typeArticleen_US

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