A case of meningitis caused by Streptococcus pyogenes in a previously healthy woman

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dc.contributor.authorUluğ M.
dc.contributor.authorUlug N.C.
dc.contributor.authorCelen M.K.
dc.contributor.authorGeyik M.F.
dc.contributor.authorAyaz C.
dc.date.accessioned2024-04-24T18:44:26Z
dc.date.available2024-04-24T18:44:26Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Streptococcus pyogenes is a well-known cause of a variety of clinical infections including local symptoms such as tonsillopharyngitis, cervical lymphadenitis, otitis media, cellulites, erysipelas, as well as more severe diseases such as scarlet fever, osteomyelitis, necrotizing fasciitis, sepsis, and toxic shock syndrome. However, acute bacterial meningitis caused by this pathogen is unusual. Objective: We report a case of group A streptococcus (GAS) meningitis in a previously healthy woman with a dramatically rapid course and fatal outcome. Case: A 41-year-old previously healthy woman presented a history of fever, headache, vomiting, and sore throat of three days' duration. Neurological examination revealed diminished consciousness and neck rigidity. The cerebrospinal fluid (CSF) was turbid with 10,000 leukocytes/mm3. Direct examination of CSF showed Gram-positive cocci in chains, and cultures yielded S. pyogenes. Blood cultures yielded growth of S. pyogenes. The patient was treated initially with ceftriaxone (4 g/day) and the control CSF examination was not changed on the third day, so vancomycin (2 g/day) was added to the treatment; however, she died on the fourth day of the treatment. Conclusion: S. pyogenes meningitis is uncommon and the incidence seems to be persistently low; nevertheless, clinicians should be aware that sporadic cases may occur and may have a fulminant course with a relevant neurological sequel. Copyright © 2009 Ulug et al.en_US
dc.identifier.endpage244en_US
dc.identifier.issn2036-6590
dc.identifier.issue3en_US
dc.identifier.pmid19759483
dc.identifier.scopus2-s2.0-67649503202
dc.identifier.scopusqualityQ2
dc.identifier.startpage241en_US
dc.identifier.urihttps://hdl.handle.net/11468/24698
dc.identifier.volume3en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofJournal of Infection in Developing Countries
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMeningitisen_US
dc.subjectMortalityen_US
dc.subjectStreptococcus Pyogenesen_US
dc.subjectTurkeyen_US
dc.titleA case of meningitis caused by Streptococcus pyogenes in a previously healthy womanen_US
dc.titleA case of meningitis caused by Streptococcus pyogenes in a previously healthy woman
dc.typeArticleen_US

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