Efficacy of mouth rinse formulation based on cetylpyridinium chloride 0.1% in the control of dental calculus buildup

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dc.contributor.authorMaharani, Diah Ayu
dc.contributor.authorRamadhani, Alia
dc.contributor.authorAdiatman, Melissa
dc.contributor.authorWimardhani, Yuniardini Septorini
dc.contributor.authorKusdhany, Linda
dc.contributor.authorRahardjo, Anyon
dc.contributor.authorYavuz, İzzet
dc.date.accessioned2024-04-24T17:58:12Z
dc.date.available2024-04-24T17:58:12Z
dc.date.issued2017
dc.departmentDicle Üniversitesi, Diş Hekimliği Fakültesi, Çocuk Diş Hekimliği Anabilim Dalıen_US
dc.description.abstractObjective: This study aimed at comparing the antiplaque, anticalculus, and antigingivitis potentials of a mouth rinse containing essential oil, alcohol, zinc, and fluoride with a mouth rinse containing cetylpyridinium chloride (CPC) 0.1% over 1-, 2-, and 3-month periods. Methods: This study was a double-blind, parallel randomized clinical trial with a 3-day run-in phase. Respondents were asked to gargle twice daily with 15 ml of mouth rinse for 30 seconds after brushing teeth. Respondents were 80 females with a mean age of 21 years, and a single dental examiner was employed throughout the study to decrease the variance. Prophylaxis was performed for all respondents before the intervention. Three mouth rinses were tested: Group 1 with the mouth rinse containing CPC 0.1%, Group 2 as the negative control, and Group 3 as the positive control with a mouth rinse containing alcohol. Evaluations were conducted by plaque index, gingival index, calculus index, and CariScreen examinations. Results: The clinical trial showed that the mouth rinse with alcohol and the mouth rinse containing CPC 0.1% were effective in inhibiting bacterial buildup (antiplaque) and have anticalculus properties, but with no statistically significant antigingivitis effect. Conclusion: It was found that the mouth rinse containing alcohol has similar effectiveness with CPC 0.1% mouth rinse, but side effects, such as a burning sensation, were reported in the alcohol-containing mouth rinse. © 2017 The Authors. Published by Innovare Academic Sciences Pvt Ltd.en_US
dc.identifier.citationMaharani, D. A., Ramadhani, A., Adiatman, M., Wimardhani, Y. S., Kusdhany, L., Rahardjo, A. ve diğerleri. (2017). Efficacy of mouth rinse formulation based on cetylpyridinium chloride 0.1% in the control of dental calculus buildup. International Journal of Applied Pharmaceutics, 9, 176-180.
dc.identifier.doi10.22159/ijap.2017.v9s1.84_91
dc.identifier.endpage180en_US
dc.identifier.issn0975-7058
dc.identifier.scopus2-s2.0-85033676831
dc.identifier.scopusqualityQ2
dc.identifier.startpage176en_US
dc.identifier.urihttps://doi.org/10.22159/ijap.2017.v9s1.84_91
dc.identifier.urihttps://hdl.handle.net/11468/23709
dc.identifier.volume9en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherInnovare Academics Sciences Pvt. Ltden_US
dc.relation.ispartofInternational Journal of Applied Pharmaceutics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnticalculusen_US
dc.subjectCetylpyridinium chlorideen_US
dc.subjectMouth rinseen_US
dc.titleEfficacy of mouth rinse formulation based on cetylpyridinium chloride 0.1% in the control of dental calculus buildupen_US
dc.titleEfficacy of mouth rinse formulation based on cetylpyridinium chloride 0.1% in the control of dental calculus buildup
dc.typeArticleen_US

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