Assessment of Technetium-99m Labeled Macroaggregated Albumin Rhinoscintigraphy for the Measurement of Nasal Mucociliary Transport Rate: Intratest, Interobserver, and Intraobserver Reproducibility

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dc.contributor.authorDostbil, Zeki
dc.contributor.authorDag, Yusuf
dc.contributor.authorCetinkaya, Ozlem
dc.contributor.authorAkdag, Mehmet
dc.contributor.authorTasdemir, Bekir
dc.date.accessioned2024-04-24T17:12:13Z
dc.date.available2024-04-24T17:12:13Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives. The measurement of mucociliary transport velocity by rhinoscintigraphy with Tc-99m-macroaggregated albumin (Tc-99m-MAA) is reliable measure of mucociliary clearance. The aim of this study is to assess the intratest, interobserver, and intraobserver reproducibility of nasal mucociliary transport rate (NMTR) measurement. Materials and Methods. Twenty-two subjects were evaluated to determine intratest reproducibility and a group of 35 subjects was examined to determine inter and intraobserver reproducibility. Rhinoscintigraphy with Tc-99m-MAA was used to measure NMTR in all study subjects. Paired NMTR measurements were compared using a range of statistical methodologies. Intraclass correlation coefficients (ICC) and repeatability coefficients and Bland-Altman plots were applied to assess the degree of intratest, interobserver, and intraobserver variation. Results. Statistical analysis of test and retest experiments demonstrated the statistical equivalence of intratest NMTR measurements, interobserver NMTR measurements, and intraobserver NMTR measurements. The intratest ICC, interobserver ICC, and intraobserver ICC were 0.96, 0.83, and 0.91, respectively, indicating that intratest and intraobserver reproducibility are excellent and interobserver reproducibility is good. Conclusions. Rhinoscintigraphy using Tc-99m-MAAresults in highly reproducible measurement of NMTR. The use of radionuclide imaging in measuring NMTR results in excellent intratest and intraobserver reproducibility and good interobserver reliability.en_US
dc.description.sponsorshipDicle University DUBAPen_US
dc.description.sponsorshipThe authors are grateful to Dicle University DUBAP for their sponsorship of English editing for this paper.en_US
dc.identifier.doi10.1155/2014/982515
dc.identifier.issn2090-908X
dc.identifier.pmid24741446
dc.identifier.urihttps://doi.org/10.1155/2014/982515
dc.identifier.urihttps://hdl.handle.net/11468/17899
dc.identifier.volume2014en_US
dc.identifier.wosWOS:000215854600070
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofScientifica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keyword]en_US
dc.titleAssessment of Technetium-99m Labeled Macroaggregated Albumin Rhinoscintigraphy for the Measurement of Nasal Mucociliary Transport Rate: Intratest, Interobserver, and Intraobserver Reproducibilityen_US
dc.titleAssessment of Technetium-99m Labeled Macroaggregated Albumin Rhinoscintigraphy for the Measurement of Nasal Mucociliary Transport Rate: Intratest, Interobserver, and Intraobserver Reproducibility
dc.typeArticleen_US

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