Impact of insulin resistance on contrast induced nephropathy in patients undergoing percutaneous coronary intervention

Basit Öğe Kaydı
dc.contributor.authorElbey, Mehmet Ali
dc.contributor.authorEvliyaoglu, Osman
dc.contributor.authorSimsek, Ziya
dc.contributor.authorOylumlu, Mustafa
dc.contributor.authorAkil, Mehmet Ata
dc.contributor.authorAydin, Mesut
dc.contributor.authorBilik, Zihni
dc.date.accessioned2024-04-24T16:10:37Z
dc.date.available2024-04-24T16:10:37Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractContrast-induced nephropathy (CIN) is a common complication following percutaneous coronary intervention (PCI). Contrast-induced nephropathy after emergency PCI in subjects with insulin resistance (IR) has not been studied before. In this prospective study we determined the relation between IR on CIN, among those undergoing PCI due to acute coronary syndrome. One hundred twenty four consecutive acute coronary syndrome patients with diabetes (N = 44), insulin resistance (N = 38) and normal glycemic metabolism (N = 42) were included in the study. They were all treated with PCI. Pre- and post procedural creatinines were measured and independent predictors of CIN were analyzed. IR was defined as a HOMA level (HOMA-IR = Serum Glucose (mg/dL) X Plasma Insulin (micro unit/mL) / 405 > 2.5. Patients with IR or diabetes had significantly higher levels of creatinine after procedure, serum cholesterol, glucose, contrast volume, hospital stay and HOMA. Female gender, frequency of CIN and multivessel disease were also higher in these patients. On the other hand they had significantly lower ejection fraction. Logistic regression analysis showed that HOMA was the single independent risk factor for CIN in patients with acute coronary syndrome treated with PCI. Insulin resistance is an independent risk factor for CIN in patients with acute coronary syndrome treated with PCI. It carries a similar risk with diabetes and proper prophylaxis should be performed.en_US
dc.identifier.doi10.1007/s13410-013-0140-4
dc.identifier.endpage44en_US
dc.identifier.issn0973-3930
dc.identifier.issn1998-3832
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84899853858
dc.identifier.scopusqualityQ3
dc.identifier.startpage40en_US
dc.identifier.urihttps://doi.org/10.1007/s13410-013-0140-4
dc.identifier.urihttps://hdl.handle.net/11468/14968
dc.identifier.volume34en_US
dc.identifier.wosWOS:000334914300008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofInternational Journal of Diabetes in Developing Countries
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Coronary Syndromeen_US
dc.subjectInsulin Resistanceen_US
dc.subjectContrast Induced Nephropathyen_US
dc.titleImpact of insulin resistance on contrast induced nephropathy in patients undergoing percutaneous coronary interventionen_US
dc.titleImpact of insulin resistance on contrast induced nephropathy in patients undergoing percutaneous coronary intervention
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu