The levels of copper, zinc and magnesium in type II diabetic patients complicated with foot infections

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dc.contributor.authorBozkurt, Fatma
dc.contributor.authorTekin, Recep
dc.contributor.authorGulsun, Serda
dc.contributor.authorSatici, Omer
dc.contributor.authorDeveci, Ozcan
dc.contributor.authorHosoglu, Salih
dc.date.accessioned2024-04-24T16:10:37Z
dc.date.available2024-04-24T16:10:37Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractChanges in levels of trace elements and magnesium (Mg) may contribute to progression of diabetes mellitus (DM) and development of the complications. The aim of this study was to measure the levels of Copper (Cu), Zinc ( Zn), Mg and Cu/Zn ratios in diabetic foot infected patients (DFI) compared to controlled diabetic patients and healthy controls. 50 patients complicated with DFI, 50 controlled diabetic patients without any complications and 100 age and sex matched healthy subjects were enrolled in the study. Fasting plasma glucose, HbA1c, Cu, Zn and Mg were measured. One-Way ANOVA test was used to compare three different groups. Correlations between different variables were analysed using Pearson's correlation coefficients(r). The mean values of Cu and Zn were higher in patients with DFI and DM compared to controls (P < 0.001). Cu/Zn ratios were higher in DM compared to DFI and control groups (P < 0.001). Serum Mg levels were lower in all diabetic patients. Elevation of Cu in DFI and DM groups was positively correlated with Cu/Zn ratios and elevation of Zn is negatively correlated. Our findings indicate an association between increased Zn concentrations and DFI.en_US
dc.identifier.doi10.1007/s13410-013-0130-6
dc.identifier.endpage169en_US
dc.identifier.issn0973-3930
dc.identifier.issn1998-3832
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84886668425
dc.identifier.scopusqualityQ3
dc.identifier.startpage165en_US
dc.identifier.urihttps://doi.org/10.1007/s13410-013-0130-6
dc.identifier.urihttps://hdl.handle.net/11468/14967
dc.identifier.volume33en_US
dc.identifier.wosWOS:000325944500007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofInternational Journal of Diabetes in Developing Countries
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSerum Metalsen_US
dc.subjectDiabetic Footen_US
dc.subjectInfectionen_US
dc.subjectOxidative Stressen_US
dc.titleThe levels of copper, zinc and magnesium in type II diabetic patients complicated with foot infectionsen_US
dc.titleThe levels of copper, zinc and magnesium in type II diabetic patients complicated with foot infections
dc.typeArticleen_US

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