Early Orbital Blood Flow Changes in Multiple Sclerosis Patients with Unilateral Acute Optic Neuritis

dc.contributor.authorAri, Seyhmus
dc.contributor.authorEkinci, Faysal
dc.contributor.authorAcar, Abdullah
dc.contributor.authorSahin, Alparslan
dc.contributor.authorCingu, Abdullah Kursat
dc.contributor.authorCinar, Yasin
dc.contributor.authorCaca, Ihsan
dc.date.accessioned2024-04-24T17:20:26Z
dc.date.available2024-04-24T17:20:26Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate orbital blood flow by using colour Doppler imaging before corticosteroid administration in multiple sclerosis patients with unilateral acute optic neuritis. Thirty multiple sclerosis patients with unilateral acute optic neuritis and 30 healthy subjects were included as the study and the control groups. The diagnosis of multiple sclerosis optic neuritis was based on clinical presentation, visually evoked potential, and magnetic resonance imaging findings. Data obtained from affected and unaffected eyes were compared with each other and the control group. Ophthalmic artery peak systolic velocity, end-diastolic velocity, resistivity index, and pulsatile index were measured in all patients before administration of systemic corticosteroid treatment and in control subjects. All parameters of blood flow obtained from affected eyes of patients who developed acute optic neuritis were significantly higher than those of the clinically uninvolved eyes of the affected patients (p < 0.001) and those of control eyes (p < 0.001). In addition, statistically significant increases were found in ophthalmic artery peak systolic velocity, end-diastolic velocity, and resistivity index of the clinically uninvolved eye of the affected patients compared with the control group (p = 0.002, p = 0.012, p = 0.013, respectively). No significant differences were found in blood flow data between left and right eyes of the control group (p > 0.05).en_US
dc.identifier.doi10.3109/01658107.2011.653704
dc.identifier.endpage41en_US
dc.identifier.issn0165-8107
dc.identifier.issn1744-506X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84859873845
dc.identifier.scopusqualityQ3
dc.identifier.startpage37en_US
dc.identifier.urihttps://doi.org/10.3109/01658107.2011.653704
dc.identifier.urihttps://hdl.handle.net/11468/19050
dc.identifier.volume36en_US
dc.identifier.wosWOS:000302900900001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTaylor & Francis Asen_US
dc.relation.ispartofNeuro-Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColour Doppler Sonographyen_US
dc.subjectMultiple Sclerosisen_US
dc.subjectOphthalmic Arteryen_US
dc.subjectOptic Neuritisen_US
dc.titleEarly Orbital Blood Flow Changes in Multiple Sclerosis Patients with Unilateral Acute Optic Neuritisen_US
dc.titleEarly Orbital Blood Flow Changes in Multiple Sclerosis Patients with Unilateral Acute Optic Neuritis
dc.typeArticleen_US

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