A comparative bio-evaluation and chemical profiles of Calendula officinalis L. extracts prepared via different extraction techniques

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dc.authorid0000000280062054en_US
dc.authorid0000-0002-4090-7227en_US
dc.contributor.authorAk, Guneş
dc.contributor.authorZengin, Gökhan
dc.contributor.authorKouadio İbrahime, Sinan
dc.contributor.authorMahomoodally, Fawzi M.
dc.contributor.authorPicot-Allain, Marie Carene Nancy
dc.contributor.authorÇakır, Oğuz
dc.contributor.authorBensari, Souheir
dc.contributor.authorYilmaz, Mustafa Abdullah
dc.contributor.authorGallo, Monica
dc.contributor.authorMontesano, Domenico
dc.date.accessioned2021-09-06T11:17:05Z
dc.date.available2021-09-06T11:17:05Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesien_US
dc.descriptionWOS:000569663900001
dc.description.abstractCalendula officinalis L., (marigold), well known for its medicinal properties, has been extensively studied for its therapeutic properties. Nonetheless, as far as the literature could establish, no study has attempted to comparatively assess the biological (antioxidant and enzyme inhibitory potential) of the flowers, leaves, and roots of C. officinalis extracted using conventional (maceration and Soxhlet extraction (SE)) and non-conventional extraction (homogenizer (HAE) and ultrasound (UAE) assisted extraction) techniques. The detailed phytochemical profile of each extract along with the concentration of specific bioactive compounds has also been established. Total phenolic content was highest for the flower extracts while flavonoid content was highest in the leaf extracts. Phytochemical profiling showed that the extraction method influenced the phytochemical composition of the extract. Nicotiflorin was identified in the flower extracts only while amentoflavone occurred only in the roots, inferring that the occurrence of bioactive compounds varies within a plant. The flower extracts showed highest antioxidant potential while the roots extracts were potent inhibitors of cholinesterase and tyrosinase. This study provides valuable data on the influence of extraction techniques on the recovery of bioactive compounds from plants. In an endeavor to scale-up extraction from plant considering the more efficient extraction method is of paramount importance. Moreover, the study highlighted the necessity to thoroughly examine the biological activities of various parts of a plant obtained via different extraction protocols.en_US
dc.identifier.citationAk, G., Zengin, G., Kouadio İbrahime, S., Mahomoodally, F. M., Picot-Allain, M. C. N., Çakır, O. ve diğerleri. (2020). A comparative bio-evaluation and chemical profiles of Calendula officinalis L. extracts prepared via different extraction techniques. Applied Sciences (Switzerland), 10(17), 5920.en_US
dc.identifier.doi10.3390/app10175920
dc.identifier.issn2076-3417
dc.identifier.issue17en_US
dc.identifier.scopus2-s2.0-85090223160
dc.identifier.scopusqualityQ1
dc.identifier.startpage5920en_US
dc.identifier.urihttps://www.mdpi.com/2076-3417/10/17/5920
dc.identifier.urihttps://hdl.handle.net/11468/7446
dc.identifier.volume10en_US
dc.identifier.wosWOS:000569663900001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorÇakır, Oğuz
dc.institutionauthorYilmaz, Mustafa Abdullah
dc.language.isoenen_US
dc.publisherMDPI AGen_US
dc.relation.ispartofApplied Sciences (Switzerland)
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCholinesteraseen_US
dc.subjectMacerationen_US
dc.subjectMarigolden_US
dc.subjectTyrosinaseen_US
dc.titleA comparative bio-evaluation and chemical profiles of Calendula officinalis L. extracts prepared via different extraction techniquesen_US
dc.titleA comparative bio-evaluation and chemical profiles of Calendula officinalis L. extracts prepared via different extraction techniques
dc.typeArticleen_US

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