Radiation induced defects in timolol: temperature dependent electron paramagnetic resonance spectroscopy analysis

Yükleniyor...
Küçük Resim

Tarih

2020

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Taylor & Francis Ltd

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Ionizing radiation-induced antihypertensive drug timolol in powder form was studied by means of electron paramagnetic resonance (EPR) technique as a function of temperature. The effect of temperature on EPR linewidth, intensity and spectra was investigated. The room temperature EPR spectra of ionizing radiation-induced timolol were recorded in dimethyl sulfoxide solution at a frozen state. The first-order kinetic mechanism rate constant of timolol was calculated. The findings on all EPR experimental data indicated that ionizing radiation-induced stable-free radical species on timolol are characterized byg= 2.0027.

Açıklama

Anahtar Kelimeler

Epr, Ionizing radiation, Timolol, Kinetics

Kaynak

Radiation Effects and Defects in Solids

WoS Q Değeri

Q4

Scopus Q Değeri

Q3

Cilt

175

Sayı

9-10

Künye

Erdamar, I. Y. D. (2020). Radiation induced defects in timolol: temperature dependent electron paramagnetic resonance spectroscopy analysis. Radiation Effects and Defects in Solids, 175(9-10), 892-897.