The role of serum osteoprotegerin and S-100 protein levels in patients with acute ischaemic stroke: Determination of stroke subtype, severity and mortality

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dc.contributor.authorÜstündaǧ, Mehmet
dc.contributor.authorOrak, Murat
dc.contributor.authorGüloǧlu, Cahfer
dc.contributor.authorTamam, Yusuf
dc.contributor.authorSayhan, Mustafa Burak
dc.contributor.authorKale, Ebru
dc.date.accessioned2024-04-24T17:56:32Z
dc.date.available2024-04-24T17:56:32Z
dc.date.issued2011
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Acil Tıp Ana Bilim Dalıen_US
dc.description.abstractThis study investigated correlations between mortality, stroke subtype and stroke severity with serum osteoprotegerin (OPG) and S-100 protein levels prior to the treatment of patients admitted to the emergency department and diagnosed with ischaemic stroke. Pretreatment serum samples were collected from patients (n = 90) to determine OPG and S-100 protein levels. Age- and sex-matched healthy individuals (n = 16) served as controls. Compared with controls, OPG and S-100 protein levels were significantly higher in the cardioembolic and atherothrombotic stroke groups. Within the stroke group, OPG levels were significantly higher in the cardioembolic and atherothrombotic stroke groups compared with the transient ischaemic attack (TIA) group. S-100 protein levels were significantly higher in the atherothrombotic stroke group than in the lacunar stroke and TIA groups, and in the cardioembolic stroke group compared with the lacunar stroke group. Serum OPG and S-100 protein levels were significantly higher in patients who died compared with survivors. In predicting stroke subtype and severity, although both OPG and S-100 protein levels were indicators, S-100 protein was more valuable for mortality prediction.en_US
dc.identifier.citationÜstündaǧ, M., Orak, M., Güloǧlu, C., Tamam, Y., Sayhan, M. B. ve Kale, E. (2011). The role of serum osteoprotegerin and S-100 protein levels in patients with acute ischaemic stroke: Determination of stroke subtype, severity and mortality. Journal of International Medical Research, 39(3), 780-789.
dc.identifier.doi10.1177/147323001103900310
dc.identifier.endpage789en_US
dc.identifier.issn0300-0605
dc.identifier.issue3en_US
dc.identifier.pmid21819709
dc.identifier.scopus2-s2.0-80052197254
dc.identifier.scopusqualityQ2
dc.identifier.startpage780en_US
dc.identifier.urihttps://doi.org/10.1177/147323001103900310
dc.identifier.urihttps://hdl.handle.net/11468/23564
dc.identifier.volume39en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSAGE Publications Ltden_US
dc.relation.ispartofJournal of International Medical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIschaemic strokeen_US
dc.subjectMortalityen_US
dc.subjectS-100 proteinen_US
dc.subjectSteoprotegerinen_US
dc.subjectStroke severityen_US
dc.titleThe role of serum osteoprotegerin and S-100 protein levels in patients with acute ischaemic stroke: Determination of stroke subtype, severity and mortalityen_US
dc.titleThe role of serum osteoprotegerin and S-100 protein levels in patients with acute ischaemic stroke: Determination of stroke subtype, severity and mortality
dc.typeArticleen_US

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