Microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure associated with acute brucellosis

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dc.contributor.authorSöker M.
dc.contributor.authorDevecioglu C.
dc.contributor.authorYaramis A.
dc.contributor.authorIpek S.
dc.contributor.authorÖzbek M.N.
dc.contributor.authorTüzün H.
dc.date.accessioned2024-04-24T18:43:58Z
dc.date.available2024-04-24T18:43:58Z
dc.date.issued2001
dc.departmentDicle Üniversitesien_US
dc.description.abstractMicroangiopathic hemolytic anemia and severe thrombocytopenia are rare in childhood brucellosis: there are few reported cases. We report our experience with a 9-year-old boy with brucella infection presenting at the onset as a microangiopathic hemolytic anemia, severe thrombocytopenia and acute renal failure with coexisting gastrointestinal bleeding and gross hematuria. Peripheral blood smear examination showed hemolytic anemia, thrombocytopenia, and leukopenia. Bone marrow aspiration specimen revealed hypercellularity, histiocytic proliferation, and hemophagocytosis of the typical features associated with Brucella infection. Results of agglutination tests for Brucella in CSF and serum were positive. The patient recovered completely after appropriate antimicrobial therapy (consisting of rifampin, doxycycline, gentamicin) and fresh-frozen plasma, platelet transfusion, and rehydration therapy. We suggest that brucellosis must be investigated when hemolytic uremic syndrome (HUS) like disease exists with no known etiology, especially in endemic countries.en_US
dc.identifier.endpage108en_US
dc.identifier.issn0885-6265
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0034968755en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage105en_US
dc.identifier.urihttps://hdl.handle.net/11468/24492
dc.identifier.volume16en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofInternational Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMicroangiopathic Hemolytic Anemiaen_US
dc.subjectRenal Failureen_US
dc.subjectS. Brucellosisen_US
dc.subjectThrombocytopeniaen_US
dc.titleMicroangiopathic hemolytic anemia, thrombocytopenia and acute renal failure associated with acute brucellosisen_US
dc.typeArticleen_US

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