Effectiveness of the cascade filtration technique in the management of inoperable leg ischemia

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dc.contributor.authorDemirtas, Sinan
dc.contributor.authorYavuz, Celal
dc.contributor.authorCaliskan, Ahmet
dc.contributor.authorKarahan, Oguz
dc.contributor.authorVural, Ahmet Hakan
dc.contributor.authorOzyazicioglu, Ahmet Fatih
dc.date.accessioned2024-04-24T17:28:00Z
dc.date.available2024-04-24T17:28:00Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: This study aims to investigate the effectiveness of the cascade filtration technique in individuals with peripheral vascular disease who are candidates for amputation. Methods: Twelve patients (9 males, 3 females; mean age 62.4 +/- 7.2 years; range 45 to 75 years) were included in the study. For the evaluation of the efficacy of this procedure, measurements of serum albumin, fibrinogen, immunoglobulin M, alpha-2 macroglobulin, low density lipoprotein (LDL) cholesterol, fibronectin, von Willebrand factor levels, blood viscosity, and transcutaneous oxygen saturation (tcPO(2)) were obtained before and after the procedure at sessions 1, 4, and 7. Results: A statistically insignificant increase in tcPO(2) values and a significant decrease in viscosity were determined (p=0.019). Fibronectin, von Willebrand factor, and viscosity levels were significantly decreased at the end of protocol, compared to baseline values. Various degrees of improvement were noted in seven of the 10 patients. After the completion of the protocol, amputation from a more distal level than previously planned was performed in three patients. Conclusion: Cascade filtration, despite its high cost, appears to be an effective treatment alternative which limits or prevents amputation.en_US
dc.identifier.doi10.5606/tgkdc.dergisi.2013.7409
dc.identifier.endpage352en_US
dc.identifier.issn1301-5680
dc.identifier.issue2en_US
dc.identifier.startpage346en_US
dc.identifier.trdizinid147800
dc.identifier.urihttps://doi.org/10.5606/tgkdc.dergisi.2013.7409
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/147800
dc.identifier.urihttps://hdl.handle.net/11468/20286
dc.identifier.volume21en_US
dc.identifier.wosWOS:000317438000013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherBaycinar Medical Publ-Baycinar Tibbi Yayinciliken_US
dc.relation.ispartofTurk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCascade Filtrationen_US
dc.subjectHemorheotherapyen_US
dc.subjectIschemic Legen_US
dc.subjectPeripheral Artery Diseaseen_US
dc.subjectRheopheresisen_US
dc.titleEffectiveness of the cascade filtration technique in the management of inoperable leg ischemiaen_US
dc.titleEffectiveness of the cascade filtration technique in the management of inoperable leg ischemia
dc.typeArticleen_US

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