Hair zinc and copper concentrations and zinc: Copper ratios in pediatric malignancies and healthy children from Southeastern Turkey

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dc.contributor.authorDonma, Mustafa Metin
dc.contributor.authorDonma, Orkide
dc.contributor.authorTaş, Mehmet Ali
dc.contributor.orcid0000-0002-4060-0583
dc.contributor.orcid0000-0001-5992-9488
dc.date.accessioned2024-04-24T17:56:04Z
dc.date.available2024-04-24T17:56:04Z
dc.date.issued1993
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractTwenty-eight healthy and forty-six children with malignancy admitted to the Pediatrics Oncology Clinic and Outpatient Clinic of Dicle University, Medical Faculty, Department of Pediatrics in 1989-1990 were included into this study. The children under investigation were divided into three groups. Group 1 consisted of 28 healthy children. Twenty-eight children with newly diagnosed malignant disease, before the start of treatment, formed Group 2. Group 3 consisted of eight of these 28 children together with 18 other children with malignancy in complete remission. 1. Mean hair zinc and copper levels, and zinc/copper values for Group 2 were found to be 100.7±6.8 ?g/g, 11.0±0.8 ?g/g, and 10.0±0.8, respectively. 2. The corresponding values for Group 3 were obtained as 143.5±6.3 ?g/g, 7.6±0.4 ?g/g, and 20.2±1.4. 3. The values for Group 1 were 142.6±4.5 ?g/g, 8.4±0.5 ?g/g, and 19.0±1.4, respectively. 4. The differences between control-active-phase and active-phase-remission groups were statistically significant (p<0.01), whereas almost the same values were obtained for the control and remission groups (p>0.05). These results were valid in cases where the comparisons of these three groups were performed also for the subgroups. It was shown that hair zinc and copper levels and zinc/copper values are useful parameters for the diagnosis and treatment of the children with malignancy because of the fact that hair reflects the integrated trace element concentrations of the body, not the present one.en_US
dc.identifier.citationDonma, M. M., Donma, O. ve Taş, M. A. (1993). Hair zinc and copper concentrations and zinc: Copper ratios in pediatric malignancies and healthy children from Southeastern Turkey. Biological Trace Element Research, 36(1), 51-63.
dc.identifier.doi10.1007/BF02783779
dc.identifier.endpage63en_US
dc.identifier.issn0163-4984
dc.identifier.issue1en_US
dc.identifier.pmid7681681
dc.identifier.scopus2-s2.0-0027513345
dc.identifier.scopusqualityQ1
dc.identifier.startpage51en_US
dc.identifier.urihttps://doi.org/10.1007/BF02783779
dc.identifier.urihttps://hdl.handle.net/11468/23244
dc.identifier.urihttps://link.springer.com/article/10.1007/BF02783779
dc.identifier.volume36en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHumana Pressen_US
dc.relation.ispartofBiological Trace Element Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHair Copperen_US
dc.subjectHair Zincen_US
dc.subjectHair zinc and copper İn children with malignancyen_US
dc.subjectHair zinc to copper ratioen_US
dc.subjectPediatric malignancyen_US
dc.subjectTrace elements İn Turkeyen_US
dc.titleHair zinc and copper concentrations and zinc: Copper ratios in pediatric malignancies and healthy children from Southeastern Turkeyen_US
dc.titleHair zinc and copper concentrations and zinc: Copper ratios in pediatric malignancies and healthy children from Southeastern Turkey
dc.typeArticleen_US

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