The characterization of phenolic compounds via LC-ESI-MS/MS, antioxidant, enzyme inhibitory activities of Salvia absconditiflora, Salvia sclarea, and Salvia palaestina: A comparative analysis

Basit Öğe Kaydı
dc.contributor.authorOnder, Alev
dc.contributor.authorIzgi, Mehmet Necat
dc.contributor.authorCinar, Ahsen Sevde
dc.contributor.authorZengin, Gokhan
dc.contributor.authorYilmaz, Mustafa Abdullah
dc.date.accessioned2024-04-24T16:18:20Z
dc.date.available2024-04-24T16:18:20Z
dc.date.issued2022
dc.departmentDicle Üniversitesien_US
dc.description.abstractSalvia L. genus, one of the medicinal and aromatic plants belonging to the Lamiaceae family, is represented by many endemic species in temperate regions worldwide. The Salvia species have plenty of usages in traditional medicine, important pharmacological effects and economic value. In this context, this study was con-ducted to evaluate the chemical profile and potential bioactivity of ethyl acetate extracts from 3 different Salvia species; Salvia absconditiflora (Salvia cryptantha-an endemic species), S. sclarea and S. palaestina collected from different localities in Anatolia. Total phenolic-flavonoid contents, antioxidant properties and enzyme inhibition experiments were investigated in tested Salvia species. The phenolic profiles were also determined by liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The analysis revealed the presence of phenolic compounds in ethyl acetate extracts such as cynaroside, rosmarinic acid, cosmosiin, luteolin, apigenin and acacetin. The highest level of phenolic components was detected in S. absconditiflora with 74.16 mg GAE/g. The best radical scavenging and reducing abilities were found in S. absconditiflora (DPPH: 251.39 mg TE/g; ABTS: 340.16 mg TE/g; CUPRAC: 496.20 mg TE/g; FRAP: 322.94 mg TE/g). Moreover, the inhibition of AChE, BChE, and alpha-amylase has also been studied. The most potent AChE inhibitory ability was recorded in S. sclarea (4.00 mg GALAE/g), followed by S. palaestina (3.38 mg GALAE/g) and S. absconditi-flora (3.01 mg GALAE/g). The extracts exhibited similar amylase inhibitory effects. These results reveal that Salvia species [S. absconditiflora (S. cryptantha), S. sclarea and S. palaestina] confirming their potential can be rich sources of promising bioactive compounds as a starting point for further analysis. In addition, it is thought that this study may be the new report for the construction of helpful databases in terms of shedding light on future research and researchers with the valuable information obtained about these economically important Salvia species. (C) 2022 SAAB. Published by Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.sajb.2022.07.030
dc.identifier.endpage322en_US
dc.identifier.issn0254-6299
dc.identifier.issn1727-9321
dc.identifier.scopus2-s2.0-85134893500
dc.identifier.scopusqualityQ1
dc.identifier.startpage313en_US
dc.identifier.urihttps://doi.org/10.1016/j.sajb.2022.07.030
dc.identifier.urihttps://hdl.handle.net/11468/16011
dc.identifier.volume150en_US
dc.identifier.wosWOS:000843015600019
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofSouth African Journal of Botany
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidanten_US
dc.subjectEnzyme Inhibitory Activityen_US
dc.subjectLc-Ms/Msen_US
dc.subjectPhenolicsen_US
dc.subjectSalviaen_US
dc.subjectS.Absconditifloraen_US
dc.subjectS. Sclareaen_US
dc.subjectS. Palaestinaen_US
dc.titleThe characterization of phenolic compounds via LC-ESI-MS/MS, antioxidant, enzyme inhibitory activities of Salvia absconditiflora, Salvia sclarea, and Salvia palaestina: A comparative analysisen_US
dc.titleThe characterization of phenolic compounds via LC-ESI-MS/MS, antioxidant, enzyme inhibitory activities of Salvia absconditiflora, Salvia sclarea, and Salvia palaestina: A comparative analysis
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu