The evaluation of the role of microwave and vitamins on rat eyes related to lipid peroxidation and tissue damage

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dc.contributor.authorAkdag, MZ
dc.contributor.authorSert, C
dc.contributor.authorErdinc, L
dc.contributor.authorDasdag, S
dc.contributor.authorBuyukbayram, H
dc.contributor.authorCelik, MS
dc.contributor.authorCakmak, SS
dc.date.accessioned2024-04-24T16:25:01Z
dc.date.available2024-04-24T16:25:01Z
dc.date.issued2002
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn the present study, the effect of low-intensity microwave radiation on rat eyes and the protective effect of some vitamins against the damage induced by microwave was investigated. 32 Wistar-albino female rats were divided into four groups (1 Control, 3 Experimental) (n=8). The rats of first experimental group were exposed to 9450 MHz microwave (2.65 mW/cm(2)) for one hour a day during 21 days. In addition to exposure with MW as first experimental group, Vitamin E and Vitamin C (150 mg/kg/day) were injected intraperitoneally to second and third experimental groups respectively during last seven days of exposure. The eyes of rats were examined daily after MW and sham exposure by an ophthalmologist biomicroscopically. After completed 21 days exposure period the rats were sacrificed under ketalar anesthesia. The rat eyes were enucleated for histopathological examination and Malondialdehyde (MDA) assay. Sero hemoragic dark brown secretion was observed in rats' conjunctiva of fist and second experimental groups after biomicroscopic examination. However, no damage was detected in the third group. Vacuolization, pleomorphism between cells and increasing of cell layers in lens fibers of all experimental groups were observed histopathologically. In the cornea of experimental groups, cellular loss, shape and size differences among cells and lack of polarity were noticed. Slight edema, congestion, desquamation in epithelial cells, separation between layers in some areas and alteration in pigment cells of retina were also determined in experimental group rats. The MDA (Malondialdehyde) levels of all experimental groups increased significantly compared to control group (P<0.05). However, no significant differences among experimental groups were observed at MDA levels (P>0.05). The temperature differences of all experimental groups were found to be significant compared to control group (P<0.05). Finally, it was determined that low-intensity long-term microwave exposure caused histopathologic alternations and lipid peroxidations on rat eyes.en_US
dc.identifier.doi10.1080/13102818.2002.10819167
dc.identifier.endpage137en_US
dc.identifier.issn1310-2818
dc.identifier.issn1314-3530
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-0036976878
dc.identifier.scopusqualityQ3
dc.identifier.startpage131en_US
dc.identifier.urihttps://doi.org/10.1080/13102818.2002.10819167
dc.identifier.urihttps://hdl.handle.net/11468/16928
dc.identifier.volume16en_US
dc.identifier.wosWOS:000180674300021
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnology & Biotechnological Equipment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keyword]en_US
dc.titleThe evaluation of the role of microwave and vitamins on rat eyes related to lipid peroxidation and tissue damageen_US
dc.titleThe evaluation of the role of microwave and vitamins on rat eyes related to lipid peroxidation and tissue damage
dc.typeArticleen_US

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