Effects of Pulsed and Sinusoidal Electromagnetic Fields on Rat Testes

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dc.contributor.authorTunik, Selcuk
dc.contributor.authorBaran, Ozlem Pamukcu
dc.contributor.authorAkpolat, Veysi
dc.contributor.authorAyaz, Ercan
dc.contributor.authorNergiz, Yusuf
dc.contributor.authorCelik, M. Salih
dc.contributor.authorYumusak, Ozkan
dc.date.accessioned2024-04-24T17:33:43Z
dc.date.available2024-04-24T17:33:43Z
dc.date.issued2020
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVE: To investigate the role of 50-Hz extremely low frequency pulsed (PEMF) and sinusoidal (SEMF) electromagnetic fields on the testis using a rat model. STUDY DESIGN: Twenty-seven male Wistar albino rats were used. The rats were divided into three groups (n=9 each): sham group, SEMF group, and PEMF group. The SEMF and PEMF groups (pulse time: 20 milliseconds, pulse frequence: 50 Hz) were subjected to 1.5 mT, 50 Hz exposure 6 hours a day, 5 days a week for 28 days in methacrylate boxes. Formalin-fixed, paraffin-embedded tissue sections were stained with H-E and PAS. In addition, E-cadherin and type IV collagen expressions were examined immunohistochemically. RESULTS: Seminiferous tubule basement membranes decreased with EMFs, especially those treated with SEMF. In addition, expression levels of E-cadherin on seminiferous epithelium decreased in PEMF and SEMF groups. The expression level of type IV collagen was also decreased in perivascular and seminiferous tubule basement membrane as compared to that in the sham group. CONCLUSION: PEMF and SEMF have adverse effects on the testis at a histopathological level. EMF leads to a decrease in E-cadherin and type IV collagen expression levels.en_US
dc.identifier.endpage84en_US
dc.identifier.issn0884-6812
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85094820953
dc.identifier.scopusqualityQ4
dc.identifier.startpage77en_US
dc.identifier.urihttps://hdl.handle.net/11468/20816
dc.identifier.volume42en_US
dc.identifier.wosWOS:000563774200002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSci Printers & Publ Incen_US
dc.relation.ispartofAnalytical and Quantitative Cytopathology and Histopathology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCadherinsen_US
dc.subjectCell Adhesionen_US
dc.subjectCollagenen_US
dc.subjectCytoplasmen_US
dc.subjectE-Cadherinen_US
dc.subjectEmf Exposureen_US
dc.subjectElectromagnetic Fieldsen_US
dc.subjectHistopathologyen_US
dc.subjectImmunohistochemistryen_US
dc.subjectType Iv Collagenen_US
dc.titleEffects of Pulsed and Sinusoidal Electromagnetic Fields on Rat Testesen_US
dc.titleEffects of Pulsed and Sinusoidal Electromagnetic Fields on Rat Testes
dc.typeArticleen_US

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