Evaluation of peripapillary microcirculation in patients with acromegaly

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dc.authorid0000-0002-3591-721Xen_US
dc.authorid0000-0002-6504-8385en_US
dc.authorid0000-0002-8206-781Xen_US
dc.authorid0000-0001-8856-0528en_US
dc.authorid0000-0002-5323-2257en_US
dc.authorid0000-0003-2348-4856en_US
dc.contributor.authorKarahan, Mine
dc.contributor.authorDemirtaş, Atılım Armağan
dc.contributor.authorHazar, Leyla
dc.contributor.authorAva, Sedat
dc.contributor.authorPekkolay, Zafer
dc.contributor.authorKeklikçi, Uğur
dc.date.accessioned2022-06-16T13:25:37Z
dc.date.available2022-06-16T13:25:37Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.descriptionPMID: 35059575
dc.description.abstractObjectives: The aim of this study was to evaluate the radial peripapillary capillary (RPC) and the optic nerve head (ONH) perfusion of patients with acromegaly using optical coherence tomography angiography (OCTA). Methods: Twenty-four eyes of 24 acromegaly patients comprised the study group and 24 eyes of 24 healthy individuals were used as a control group. The ONH and RPC vascular density (VD) was measured for each patient using OCTA. The insulin-like growth factor 1 (IGF-1) levels were also recorded and compared. Results: The VD of the inferior nasal ONH and nasal RPC was significantly lower in the acromegaly group than in the control group (p=0.047 and p=0.001, respectively). There was a significant negative correlation between the VD of the superior nasal ONH and the IGF-1 level (r=-0.283, p=0.038). Conclusion: The ONH and RPC VD values measured using OCTA were segmentally different in the acromegaly group compared with those of the control group. This method of non-invasive quantitative analysis of retinal perfusion using OCTA may be useful for future studies involving patients with acromegaly.en_US
dc.identifier.citationKarahan, M., Demirtaş, A. A., Hazar, L., Ava, S., Pekkolay, Z., Keklikçi, U. ve diğerleri. (2021). Evaluation of peripapillary microcirculation in patients with acromegaly. Beyoğlu Eye Journal, 6(4), 285-289.en_US
dc.identifier.doi10.14744/bej.2021.48343
dc.identifier.endpage289en_US
dc.identifier.issn2459-1777
dc.identifier.issn2587-0394
dc.identifier.issue4en_US
dc.identifier.startpage285en_US
dc.identifier.trdizinid511845
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TlRFeE9EUTFOUT09
dc.identifier.urihttps://hdl.handle.net/11468/10010
dc.identifier.volume6en_US
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorKarahan, Mine
dc.institutionauthorHazar, Leyla
dc.institutionauthorAva, Sedat
dc.institutionauthorPekkolay, Zafer
dc.institutionauthorKeklikçi, Uğur
dc.language.isoenen_US
dc.publisherKARE yayıncılıken_US
dc.relation.ispartofBeyoğlu Eye Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcromegalyen_US
dc.subjectOptical coherence tomography angiographyen_US
dc.subjectOptic nerve headen_US
dc.subjectVascular densityen_US
dc.titleEvaluation of peripapillary microcirculation in patients with acromegalyen_US
dc.titleEvaluation of peripapillary microcirculation in patients with acromegaly
dc.typeArticleen_US

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