Determination of antioxidant, cytotoxic, anticholinesterase, antiurease, antityrosinase, and antielastase activities and aroma, essential oil, fatty acid, phenolic, and terpenoid-phytosterol contents of Salvia poculata

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dc.authorid0000-0002-0988-9462en_US
dc.contributor.authorYener, İsmail
dc.date.accessioned2024-04-18T12:47:21Z
dc.date.available2024-04-18T12:47:21Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractIn this study, the essential oil, aroma, fatty acid, terpeneoid and phenolic contents of Salvia poculata were investigated. Additionally, antioxidant, toxic-cytotoxic activities of essential oil and the ethanol extracts were determined. Moreover, anticholinesterase, antiurease, antityrosinase and antielastase enzymes inhibition activities of the extracts were examined. In GC–MS studies, germacrene D (20.07 %), caryophyllene (17.57 %) and tricosanoic acid (17.01 %) were determined as the major components for essential oil, aroma and fatty acid compositions, respectively. Besides, according to the GC–MS and LC–MS/MS results, this species was determined to contain considerable amounts of ferruginol (9292.9 μg analyte/g extract) and rosmarinic acid (15612.08 μg analyte/g extract). In parallel with the high total phenolic and rosmarinic content of the species, its ethanol extract has a high antioxidant potential. It was determined that the species was not active against acetylcholinesterase enzyme, however, the root ethanol extract showed good activity (Inhibition%: 63.01 ± 1.12) against butyrylcholinesterase enzyme. All extracts of the species were found to have fairly high anti-urease activity (Inhibition%: 89.67 ± 0.72), however, all extracts of S. poculata showed moderate and similar activities in anti-tyrosinase and antielastase activity assays. It can be deducted that the species has potential in food preservative and pharmaceutical industry due to its total phenolic and rosmarinic acid content, antioxidant capacity, antiurease and antibutyrylcholinesterase enzymes activity.en_US
dc.identifier.citationYener, İ. (2020). Determination of antioxidant, cytotoxic, anticholinesterase, antiurease, antityrosinase, and antielastase activities and aroma, essential oil, fatty acid, phenolic, and terpenoid-phytosterol contents of Salvia poculata. Industrial Crops and Products, 155, 1-12.en_US
dc.identifier.doi10.1016/j.indcrop.2020.112712
dc.identifier.endpage12en_US
dc.identifier.issn0926-6690
dc.identifier.scopus2-s2.0-85088401570
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0926669020306294?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/11468/13927
dc.identifier.volume155en_US
dc.identifier.wosWOS:000571867700010
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYener, İsmail
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofIndustrial Crops and Products
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectS. poculataen_US
dc.subjectFerruginolen_US
dc.subjectRosmarinic aciden_US
dc.subjectEnzyme activitiesen_US
dc.subjectLC–MS/MSen_US
dc.subjectGC–MSen_US
dc.titleDetermination of antioxidant, cytotoxic, anticholinesterase, antiurease, antityrosinase, and antielastase activities and aroma, essential oil, fatty acid, phenolic, and terpenoid-phytosterol contents of Salvia poculataen_US
dc.titleDetermination of antioxidant, cytotoxic, anticholinesterase, antiurease, antityrosinase, and antielastase activities and aroma, essential oil, fatty acid, phenolic, and terpenoid-phytosterol contents of Salvia poculata
dc.typeArticleen_US

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