Synthesis, reactivity and biological properties of methoxy-activated indoles

dc.contributor.authorŞengül, İbrahim F.
dc.contributor.authorBingül, Murat
dc.contributor.authorKandemir, Hakan
dc.contributor.authorKumar, Naresh
dc.contributor.authorBlack, David StC.
dc.contributor.editorAttanasi, O.A.
dc.contributor.editorGabriele, B.
dc.contributor.editorMerino, P.
dc.contributor.editorSpinelli, D.
dc.date.accessioned2022-03-10T11:35:02Z
dc.date.available2022-03-10T11:35:02Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bililmleri Bölümüen_US
dc.descriptionWOS:000758279000008
dc.description.abstractIndoles continue to play a central role in the development of new structures of chemical and biological interest. They are the source of numerous biologically active natural products by virtue of their derivation from tryptophan units which are essential to peptide, protein and enzyme structures. Although the indole unit is electron rich and displays a wide range of reactivity, many naturally-occurring indoles contain methoxy substituents, which enhance their reactivity. The synthesis of methoxyindoles has also become a strategy for diversifying the regiochemical behaviour of indoles. This review brings together a wide range of information relating to indoles incorporating one, two, or three methoxy groups. It deals with aspects of synthesis, reactivity, and biological activity as well as summarizing the scope of important natural products.en_US
dc.identifier.citationŞengül, İ.F., Bingül, M., Kandemir, H., Kumar, N. ve Black, D.S. (2021). Synthesis, reactivity and biological properties of methoxy-activated indoles. (Attanasi, O.A., Gabriele, B., Merino, P. ve Spinelli, D., Ed.), (pp. 162-212). Rome: Society Chimica Italiana.en_US
dc.identifier.doi10.17374/targets.2022.25.162
dc.identifier.endpage212en_US
dc.identifier.isbn978-88-94952-27-8
dc.identifier.scopus2-s2.0-85124719509
dc.identifier.scopusqualityN/A
dc.identifier.startpage162en_US
dc.identifier.urihttps://www.soc.chim.it/sites/default/files/ths/25/chapter_8.pdf
dc.identifier.urihttps://hdl.handle.net/11468/9371
dc.identifier.wosWOS:000758279000008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorBingül, Murat
dc.language.isoenen_US
dc.publisherSociety Chimica Italianaen_US
dc.relation.ispartofChemistry and Properties
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStem bark alkaloidsen_US
dc.subjectOne-pot synthesisen_US
dc.subjectAntiinflammatory activityen_US
dc.titleSynthesis, reactivity and biological properties of methoxy-activated indolesen_US
dc.titleSynthesis, reactivity and biological properties of methoxy-activated indoles
dc.typeBook Chapteren_US

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