Aminophylline reversal of flunitrazepam sedation

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dc.contributor.authorGurel A.
dc.contributor.authorElevli M.
dc.contributor.authorHamulu A.
dc.date.accessioned2024-04-24T18:44:11Z
dc.date.available2024-04-24T18:44:11Z
dc.date.issued1987
dc.departmentDicle Üniversitesien_US
dc.description.abstractSeventeen otherwise healthy patients were given either intravenous physiologic saline, 5 ml, aminophylline, 2 mg/kg, randomly 30 min after they were given intravenous flunitrazepam in doses adequate to produce sleep and sedation during spinal anesthesia for anorectal surgery. In the control group, mean sedation scores were 1.8 ± 0.3 and 1.0 ± 0.4 15 and 45 min after injection of placebo. Fifteen and 45 min after the injection of aminophylline the mean scores of sedation were 0.4 ± 0.2 and 0.2 ± 0.2, respectively. Even though the patients in both groups appeared to be equally alert and responsive after 75 min, Trieger tests revealed that psychomotor function was still significantly impaired in the control group 90 min after the injection of placebo. The amnesic effects of flunitrazepam were not affected by aminophylline. Aminophylline may be used to reverse the sedative and psychomotor effects of flunitrazepam.en_US
dc.identifier.endpage336en_US
dc.identifier.issn0003-2999
dc.identifier.issue4en_US
dc.identifier.pmid3565796
dc.identifier.scopus2-s2.0-0023272367
dc.identifier.scopusqualityQ1
dc.identifier.startpage333en_US
dc.identifier.urihttps://hdl.handle.net/11468/24600
dc.identifier.volume66en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofAnesthesia and Analgesia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleAminophylline reversal of flunitrazepam sedationen_US
dc.titleAminophylline reversal of flunitrazepam sedation
dc.typeArticleen_US

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