The Increase of The Mean Platelet Volume in Patients With Intracerebral Haemorrhage

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dc.contributor.authorArikanoglu, Adalet
dc.contributor.authorCevik, Mehmet Ugur
dc.contributor.authorUzar, Ertugrul
dc.contributor.authorAcar, Abdullah
dc.contributor.authorAkil, Esref
dc.contributor.authorEkici, Faysal
dc.contributor.authorTasdemir, Nebahat
dc.date.accessioned2024-04-24T17:24:29Z
dc.date.available2024-04-24T17:24:29Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: The mean platelet volume (MPV) is a biomarker of platelet function and activity. The influence of platelet function disorders on the aetiology of intracerebral haemorrhages (ICH) and mortality is not clear yet. The purpose of this study is to investigate the change in the MPV values in patients with ICH and to observe its influence on mortality in a retrospective manner. Material and Method: Sixty-six patients with intracerebral haemorrhage (32 males, 34 females; mean age: 61.9 +/- 16.9) were enrolled in the study. Patients with ICH were divided into two groups as those who died within the first 10 days and those who survived. The MPV values and the haematoma volumes were compared between the groups. Also, the MPV values and platelet counts of the patients with ICH were compared with the values of healthy volunteers from similar age and sex groups (27 males, 17 females; mean age: 59.9 +/- 3.2). Results: The MPV values of the patients with ICH measured within 24 hours following the intracerebral haemorrhage (8.33 +/- 1.27 fl) were statistically significantly higher than the MPV values of the control group (7.76 +/- 1.14 fl) (p=0.018). The platelet counts of the patients with ICH also measured with in the first 24 hours (235.8 +/- 94.9 x 10(3)/mL) were statistically significantly lower than the platelet counts of the control group (279.1 +/- 94.9 x 10(3)/mL) (p=0.022). No statistically significant difference in terms of the MPV values and platelet counts was observed between the patients with ICH who died within the first 10 days and those who survived (p>0.05). However, the difference observed in the haematoma volume between the patients with ICH who died within the first 10 days (31.1 +/- 33.7 ml) and those who survived (8.7 +/- 13.4 ml) was statistically significant (p<0.001). No correlation was found between the haematoma volume and the MPV value in the patients with ICH. Discussion: The increase, observed in the mean platelet volume in patients with ICH, may point to a disorder in the platelet function. No relationship was found between the increase in the MPV and the mortality rates.en_US
dc.identifier.doi10.4274/Tnd.05325
dc.identifier.endpage61en_US
dc.identifier.issn1301-062X
dc.identifier.issn1309-2545
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84863736586
dc.identifier.scopusqualityQ4
dc.identifier.startpage54en_US
dc.identifier.urihttps://doi.org/10.4274/Tnd.05325
dc.identifier.urihttps://hdl.handle.net/11468/19697
dc.identifier.volume18en_US
dc.identifier.wosWOS:000217530400002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofTurkish Journal of Neurology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIntracerebral Haemorrhageen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectMortalityen_US
dc.titleThe Increase of The Mean Platelet Volume in Patients With Intracerebral Haemorrhageen_US
dc.titleThe Increase of The Mean Platelet Volume in Patients With Intracerebral Haemorrhage
dc.typeArticleen_US

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