Effect of dietary zearalenone on the performance, reproduction tract and serum biochemistry in young rats
dc.contributor.author | Denli, Muzaffer | |
dc.contributor.author | Carlos Blandon, Juan | |
dc.contributor.author | Salado, Silvia | |
dc.contributor.author | Elena Guynot, Maria | |
dc.contributor.author | Francisco Perez, Jose | |
dc.date.accessioned | 2024-04-24T16:24:45Z | |
dc.date.available | 2024-04-24T16:24:45Z | |
dc.date.issued | 2017 | |
dc.department | Dicle Üniversitesi | en_US |
dc.description.abstract | The present study was conducted to determine the toxic dose response of a chronic dietary Zearalenone (ZEA) in weaned young rats. Sixty, 21-day-old, Sprague Dawley female rats were randomly allocated to five groups of four replicate cages containing three rats. Rats were fed diets with increasing amounts of ZEA (0, 0.5, 0.9, 1.8 and 3.6 mg/kg) for 4 weeks. Daily feed intake was reduced (P < .05) by feeding the ZEA diets with 0.9 and 3.6 mg ZEA/kg feed. Rats fed the diet containing 1.8 mg ZEA/kg increased (P < .05) the body weight gain (BWG) and reduced (P < .05) feed conversion rate (FCR) as compared to the control group. The two highest levels of dietary ZEA also increased (P < .05) the weight of the uterus. However, ovaries' weight, timing of vaginal opening and the inter-oestrous interval were not affected by increasing the doses of dietary ZEA (P > .05). Similarly, serum concentrations of total protein, follicle-stimulating hormone and alanine aminotransferase, aspartate aminotransferase and alkaline phosphate activities were not altered by the ZEA treatments. In conclusion, our results indicated that a chronic dietary consumption of ZEA at concentrations of 1.8 mg ZEA/kg increases the BWG and the uterus weight of weaning female rats. | en_US |
dc.description.sponsorship | Torres Quevedo [PTQ2004-0869]; [299 PROFIT FIT-0300-2003-335]; [CDTI 20050012] | en_US |
dc.description.sponsorship | This work, part of MONALISA EUREKA Project E! 3025, was supported by 299 PROFIT FIT-0300-2003-335, CDTI 20050012, and Torres Quevedo PTQ2004-0869. | en_US |
dc.identifier.doi | 10.1080/09712119.2016.1251929 | |
dc.identifier.endpage | 622 | en_US |
dc.identifier.issn | 0971-2119 | |
dc.identifier.issn | 0974-1844 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.scopus | 2-s2.0-85034747877 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.startpage | 619 | en_US |
dc.identifier.uri | https://doi.org/10.1080/09712119.2016.1251929 | |
dc.identifier.uri | https://hdl.handle.net/11468/16842 | |
dc.identifier.volume | 45 | en_US |
dc.identifier.wos | WOS:000416541400007 | |
dc.identifier.wosquality | Q3 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.language.iso | en | en_US |
dc.publisher | Taylor & Francis Ltd | en_US |
dc.relation.ispartof | Journal of Applied Animal Research | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Zearalenone | en_US |
dc.subject | Uterus | en_US |
dc.subject | Ovaries | en_US |
dc.subject | Biochemistry | en_US |
dc.subject | Weaning Rats | en_US |
dc.title | Effect of dietary zearalenone on the performance, reproduction tract and serum biochemistry in young rats | en_US |
dc.title | Effect of dietary zearalenone on the performance, reproduction tract and serum biochemistry in young rats | |
dc.type | Article | en_US |