Dosimetric comparison of prostate radiotherapy between pelvic node-positive and node-negative patients
Yükleniyor...
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
IJRR-Iranian Journal Radiation Research
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: The importance of dose in prostate radiotherapy is well known, and the dosimetric effects of radiotherapy in node-positive or node-negative patients with prostate cancer have become an important issue. Materials and Methods: Helical tomotherapy (TH) plans of 19 pelvic node-positive [THpn(+) plan] or node-negative [THpn(-) plan] patients with prostate cancer were retrospectively created in our clinic. In these plans, the beam angle was set to cover the planning target volume (PTV) of prostate cancer and minimize the dose to the organs at risk, including the bladder, rectum, femoral head, and bowel. Results: There were no differences in the conformity index, D-max, D-mean, and homogeneity index of PTV between the THpn (+) and THpn (-) plans (p>0.05). However, V95 in the THpn (+) plan was lower than that in the THpn (-) plan (p=0.017). Moreover, D-max, V75, V70, V65, V60, V50, V40, V30, and V20 for the rectum were not significantly different between the two plans (p>0.05), whereas D-mean was significantly different (p=0.025). D-max, V70, V65, and V60 for the bladder were not significantly different between the two plans (p>0.05), whereas V55, V50, V40, and V30 were significantly different (p<0.05). Finally, D-max and V50 for the femoral head and bowel were significantly different between the two plans (p<0.05). Conclusion: The THpn (+)] and [THpn(-) plans achieved acceptable target dose coverage in prostate radiotherapy.
Açıklama
WOS:000717866000030
Anahtar Kelimeler
Prostate cancer, TomoHelical, Irradiation
Kaynak
International Journal of Radiation Research
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
19
Sayı
4
Künye
Zincircioglu, S.B., Doğan, M.H., Kaya, M.A. ve Teke, F. (2021). Dosimetric comparison of prostate radiotherapy between pelvic node-positive and node-negative patients. International Journal of Radiation Research, 19(4), 1009-1014.
