PLASMA D-DIMER LEVELS IN ACUTE ISCHEMIC STROKE: ASSOCIATION WITH MORTALITY, STROKE TYPE AND PROGNOSIS

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dc.contributor.authorUestuendag, Mehmet
dc.contributor.authorOrak, Murat
dc.contributor.authorGueloglu, Cahfer
dc.contributor.authorTamam, Yusuf
dc.contributor.authorSayhan, Mustafa Burak
dc.date.accessioned2024-04-24T17:40:17Z
dc.date.available2024-04-24T17:40:17Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: The purpose of this study is to examine the correlation between mortality, stroke sub-types, neurological disability and D-Dimer values measured before a specific treatment is given to patients in the emergency department. Material and Method: In the first 24 hours after stroke symptoms started and before anticoagulant treatment started, the serum D-Dimer levels of every patient were examined. The stroke sub-type of every patient was determined according to TOAST criteria and clinical classification was made according to the Oxfordshire Community Stroke Project (OCSP). The Rankin scale was used to determine the neurological disability of the surviving patients. Results: Ninety one patients were included in the study. There was a significant difference between the D-Dimer levels of patients who died and who survived (4.50+2.80 and 1.39+1.36 ng/ml respectively, p=0.003). According to the TOAST criteria, average D-dimer levels of cardioembolic and atherothrombotic stroke patients were higher than the control group. (4.35 +/- 3.03/ 3.11 +/- 1.69 and 0.43 +/- 0.26 respectively, p=0.000). According to OCSP classification, average D-dimer levels of patients with total anterior circulation infract (TOCI) and partial anterior circulation infract (PACI) were higher than the control group, (3.67 +/- 2.14, 4 +/- 3.03 and 0.43 +/- 0.26, respectively, p=0.000). The evaluation of surviving stroke patients in terms of neurological disability revealed that average D-dimer levels of patients with serious neurological disability (Rankin score=3-5) were higher than patients with slight neurological disability (Rankin score=0 and Rankin score=12), (2.85 +/- 1.69; 0.79 +/- 0.56; 0.81 +/- 0.44 respectively, p=0.000). Conclusion: We reached the conclusion that D-dimer levels in the acute period can be a leading factor for clinicians in predicting the direct results of cerebral infarct and deciding the type of treatment.en_US
dc.identifier.endpage42en_US
dc.identifier.issn1305-2381
dc.identifier.issue2en_US
dc.identifier.startpage37en_US
dc.identifier.urihttps://hdl.handle.net/11468/21722
dc.identifier.volume6en_US
dc.identifier.wosWOS:000281404900007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherNobel Ilacen_US
dc.relation.ispartofNobel Medicus
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStrokeen_US
dc.subjectD-Dimeren_US
dc.subjectMortalityen_US
dc.subjectNeurological Disabilityen_US
dc.titlePLASMA D-DIMER LEVELS IN ACUTE ISCHEMIC STROKE: ASSOCIATION WITH MORTALITY, STROKE TYPE AND PROGNOSISen_US
dc.titlePLASMA D-DIMER LEVELS IN ACUTE ISCHEMIC STROKE: ASSOCIATION WITH MORTALITY, STROKE TYPE AND PROGNOSIS
dc.typeArticleen_US

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