Risk factors for persistent gestational trophoblastic neoplasia

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dc.contributor.authorKuyumcuoglu U.
dc.contributor.authorGuzel A.I.
dc.contributor.authorErdemoglu M.
dc.contributor.authorCelik Y.
dc.date.accessioned2024-04-24T18:45:56Z
dc.date.available2024-04-24T18:45:56Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractThis retrospective study evaluated the risk factors for persistent gestational trophoblastic disease (GTN) and determined their odds ratios. This study included 100 cases with GTN admitted to our clinic. Possible risk factors recorded were age, gravidity, parity, size of the neoplasia, and ?-human chorionic gonadotropin levels (?-hCG) before and after the procedure. Statistical analyses consisted of the independent sample t-test and logistic regression using the statistical package SPSS ver. 15.0 for Windows (SPSS, Chicago, IL, USA). Twenty of the cases had persistent GTN, and the differences between these and the others cases were evaluated. The size of the neoplasia and histopathological type of GTN had no statistical relationship with persistence, whereas age, gravidity, and ?-hCG levels were significant risk factors for persistent GTN (p < 0.05). The odds ratios (95% confidence interval (CI)) for age, gravidity, and pre- and post-evacuation ?-hCG levels determined using logistic regression were 4.678 (0.97-22.44), 7.315 (1.16-46.16), 2.637 (1.41-4.94), and 2.339 (1.52-3.60), respectively. Patient age, gravidity, and ?-hCG levels were risk factors for persistent GTN, whereas the size of the neoplasia and histopathological type of GTN were not significant risk factors. © 2010 Old City Publishing, Inc.en_US
dc.identifier.endpage84en_US
dc.identifier.issn1359-4117
dc.identifier.issue1en_US
dc.identifier.pmid21275269
dc.identifier.scopus2-s2.0-79251473712
dc.identifier.scopusqualityQ4
dc.identifier.startpage81en_US
dc.identifier.urihttps://hdl.handle.net/11468/24974
dc.identifier.volume9en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofJournal of Experimental Therapeutics and Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGestational Trophoblastic Neoplasmsen_US
dc.subjectPersistenten_US
dc.subjectRisk Factorsen_US
dc.titleRisk factors for persistent gestational trophoblastic neoplasiaen_US
dc.titleRisk factors for persistent gestational trophoblastic neoplasia
dc.typeArticleen_US

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