Primer pterjium eksizyonunda amnion membran grefti ve intraoperatif mitomisin C yöntemlerinin karşılaştırılması
Yükleniyor...
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Dicle Üniversitesi Tıp Fakültesi
Erişim Hakkı
Attribution-NonCommercial 3.0 United States
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
Primer pterjium tedavisinde insan amnion membranı uygulanmasının etkinlik ve güvenilirliğinin, Mitomisin C uygulanması ile karşılaştırılması amaçlandı. Primer pterjium tanısı konan 60 hastanın 60 gözü çalışmaya dahil edildi. Hastalar rastgele iki gruba ayrılarak, 30 hastanın 30 gözüne, pterjium eksizyonu
ile intraoperatif 0.2 mg/ml Mitomisin C uygulandı. Diğer 30 göze ise pterjium eksizyonu ve amnion membranı uygulandı. Amnion membran uygulanan grupta %6.66, Mitomisin C grubunda ise %16.66 nüks gelişti. İki grup nüks açısından karşılaştırıldığında istatiksel olarak anlamlı fark saptanmadı (p > 0.05). Komplikasyon olarak, amnion membran grubunda bir hastada (%3.33) postoperatif erken dönemde sütür açılması saptanırken, Mitomisin C grubunda bir hastada (%3.33) skleral erime, bir hastada da (%3.33) punktat epiteliyopati saptandı. Gruplar komplikasyon yönünden karşılaştırıldıklarında aralarında istatistiksel olarak anlamlı fark bulunmadı (p > 0.05). Her ne kadar iki grup arasında komplikasyon ve nüks açısından istatistiksel olarak anlamlı fark görülmese de; primer pterjium cerrahisinde amnion membran
kullanımının intraoperatif Mitomisin C kullanımından daha güvenilir olduğu kanatine varıldı.
To evaluate and compare the effectiveness and safety of the human amniotic membrane graft with intraoperative application of Mitomycin C in primary pterygium surgery. In 60 consecutive patients, 60 eyes were included in the study. The patients were randomly divided into two groups, primary pterygium excision with intraoperative Mitomycin C (0.2 mg/ml) were applied to the 30 patients and amniotic membrane grafts were applied to the other 30 patients. Recurrence was detected in two patients (%6.66) who received amniotic membrane grafts, and in five patients (%16.66) who received primary pterygium excision with intraoperative Mitomycin C. No statistical difference was observed between groups according to the reccurence (p > 0.05). Suture lysis in early postoperative period was detected in one patient (%3.33) who received amniotic membrane grafts. Scleral melting was developed in one patient (%3.33) and punctate epitheliopathy was developed in one patient (%3.33) who received primary pterygium excision with intraoperative Mitomycin C. No statistical difference was observed between groups according to the complications (p > 0.05). Although no statistical difference was observed between two groups according to complication and reccurence, amniotic membrane graft method was safer than primary pterygium excision with intraoperative Mitomycin C.
To evaluate and compare the effectiveness and safety of the human amniotic membrane graft with intraoperative application of Mitomycin C in primary pterygium surgery. In 60 consecutive patients, 60 eyes were included in the study. The patients were randomly divided into two groups, primary pterygium excision with intraoperative Mitomycin C (0.2 mg/ml) were applied to the 30 patients and amniotic membrane grafts were applied to the other 30 patients. Recurrence was detected in two patients (%6.66) who received amniotic membrane grafts, and in five patients (%16.66) who received primary pterygium excision with intraoperative Mitomycin C. No statistical difference was observed between groups according to the reccurence (p > 0.05). Suture lysis in early postoperative period was detected in one patient (%3.33) who received amniotic membrane grafts. Scleral melting was developed in one patient (%3.33) and punctate epitheliopathy was developed in one patient (%3.33) who received primary pterygium excision with intraoperative Mitomycin C. No statistical difference was observed between groups according to the complications (p > 0.05). Although no statistical difference was observed between two groups according to complication and reccurence, amniotic membrane graft method was safer than primary pterygium excision with intraoperative Mitomycin C.
Açıklama
Anahtar Kelimeler
Amnion membran, Mitomisin C, Pterjium, Amniotic membrane, Mitomycin C, Pterygium
Kaynak
Dicle Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
35
Sayı
1
Künye
Bilek, B., Keklikçi, U., Şakalar, Y.B., Ünlü, M.K. ve Çaçan, İ. (2008). Primer pterjium eksizyonunda amnion membran grefti ve intraoperatif mitomisin C yöntemlerinin karşılaştırılması. Dicle Tıp Dergisi, 35(1), 44-49.
