The effects of vitamin E on gastric ulcers and gastric mucosal barrier in stress induced rats

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dc.contributor.authorKurt, Doğan
dc.contributor.authorCanoruç, Fikri
dc.contributor.authorDenli, Orhan
dc.contributor.authorKanay, Zeki
dc.contributor.authorŞermet, Abdurrahman
dc.contributor.authorGüzel, Cihat
dc.date.accessioned2024-04-24T18:56:41Z
dc.date.available2024-04-24T18:56:41Z
dc.date.issued1998
dc.departmentDicle Üniversitesien_US
dc.description.abstractEffects of vitamin E on gastric ulcers gastric mucosal barrier were investigated in cold + restraint stress (CRS) induced rats. In this study 21 males two month old Swiss Albino Rats were used. Stress treated rats significantly decreased mucus and phospholipid content of gastric mucosa (p<0.01,P<O.Ol). Vitamin E was administered orally in the dose of 100 mg/kg body weight thirty min. before stress. Vitamin E reduced significantly gastric ulceration (p<0.01). Moreover, it significanly protected mucus secretion and phospholipid content of gastric mucosa in rats (p<0.01, p<0.01, respectively). These results indicate that extrinsic application of vitamin E may strengthen gastric mucosal barrier in rats.en_US
dc.identifier.endpage21en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue1en_US
dc.identifier.startpage19en_US
dc.identifier.trdizinid6245
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/6245
dc.identifier.urihttps://hdl.handle.net/11468/25384
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe effects of vitamin E on gastric ulcers and gastric mucosal barrier in stress induced ratsen_US
dc.titleThe effects of vitamin E on gastric ulcers and gastric mucosal barrier in stress induced rats
dc.typeOtheren_US

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