The effects of vitamin E on gastric ulcers and gastric mucosal barrier in stress induced rats

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Tarih

1998

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Effects of vitamin E on gastric ulcers gastric mucosal barrier were investigated in cold + restraint stress (CRS) induced rats. In this study 21 males two month old Swiss Albino Rats were used. Stress treated rats significantly decreased mucus and phospholipid content of gastric mucosa (p<0.01,P<O.Ol). Vitamin E was administered orally in the dose of 100 mg/kg body weight thirty min. before stress. Vitamin E reduced significantly gastric ulceration (p<0.01). Moreover, it significanly protected mucus secretion and phospholipid content of gastric mucosa in rats (p<0.01, p<0.01, respectively). These results indicate that extrinsic application of vitamin E may strengthen gastric mucosal barrier in rats.

Açıklama

Anahtar Kelimeler

Kaynak

Turkish Journal of Medical Sciences

WoS Q Değeri

Scopus Q Değeri

Cilt

28

Sayı

1

Künye