The effects of vitamin E on gastric ulcers and gastric mucosal barrier in stress induced rats
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Tarih
1998
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Effects of vitamin E on gastric ulcers gastric mucosal barrier were investigated in cold + restraint stress (CRS) induced rats. In this study 21 males two month old Swiss Albino Rats were used. Stress treated rats significantly decreased mucus and phospholipid content of gastric mucosa (p<0.01,P<O.Ol). Vitamin E was administered orally in the dose of 100 mg/kg body weight thirty min. before stress. Vitamin E reduced significantly gastric ulceration (p<0.01). Moreover, it significanly protected mucus secretion and phospholipid content of gastric mucosa in rats (p<0.01, p<0.01, respectively). These results indicate that extrinsic application of vitamin E may strengthen gastric mucosal barrier in rats.
Açıklama
Anahtar Kelimeler
Kaynak
Turkish Journal of Medical Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
28
Sayı
1
