The relationship between coenzyme Q10 and severity of coronary artery disease

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dc.contributor.authorBüyükkaya E.
dc.contributor.authorEvliyaoğlu O.
dc.contributor.authorIslamoğlu Y.
dc.contributor.authorCil H.
dc.contributor.authorKarakaş M.F.
dc.contributor.authorAkçay A.B.
dc.contributor.authorBilen P.
dc.date.accessioned2024-04-24T18:45:44Z
dc.date.available2024-04-24T18:45:44Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim To evaluate the relationship between the levels of plasma coenzyme Q10 (CoQ10), a known antioxidant, and severity of the coronary atherosclerosis (AS) measured by Gensini score. Methods Patients with coronary artery disease (CAD) were enrolled to the study between 2010 and 2011 in cardiology outpatient clinics. They were admitted for diagnostic coronary angiography or angioplasty for typical indications. The Gensini scoring system was used to calculate CAD severity. Serum CoQ10, total cholesterol (TC), HDL cholesterol, LDL cholesterol, and triglyceride levels were assessed. Results One hundred thirteen subjects (83 CAD, 30 controls) were included. The patients with CAD were separated into three groups according to Gensini score. The serum levels of CoQ10, CoQ10/ TC, CoQ10/LDL-C, CoQ10/TG rates in the subjects of mild and severe AS groups were significantly lower than the control group (p<0.016 for all control vs. AS group comparisons). There were no significant differences in serum levels of CoQ10 and CoQ10/ TC, CoQ10/LDL-C, CoQ10/TG rates between the mild and severe AS groups. Conclusion This study revealed that although the serum CoQ10 levels were lower in stable CAD, there was no relationship between the severity of CAD and serum CoQ10 levels in patients with stable angina pectoris.en_US
dc.identifier.endpage233en_US
dc.identifier.issn1840-0132
dc.identifier.issue2en_US
dc.identifier.pmid23892836
dc.identifier.scopus2-s2.0-84880751050
dc.identifier.scopusqualityQ2
dc.identifier.startpage229en_US
dc.identifier.urihttps://hdl.handle.net/11468/24839
dc.identifier.volume10en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofMedicinski Glasnik
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidanten_US
dc.subjectAtherosclerosisen_US
dc.subjectGensini Scoreen_US
dc.titleThe relationship between coenzyme Q10 and severity of coronary artery diseaseen_US
dc.titleThe relationship between coenzyme Q10 and severity of coronary artery disease
dc.typeArticleen_US

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