Colorectal Cancer in Patients Aged ?30 Years: 17 Years of Experience

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dc.contributor.authorOzaydin, Sukru
dc.contributor.authorAtas, Erman
dc.contributor.authorTanriseven, Mustafa
dc.contributor.authorKaplan, Muhammed A.
dc.contributor.authorHartendorp, Patrick
dc.contributor.authorUnlu, Aytekin
dc.contributor.authorPetrone, Patrizio
dc.date.accessioned2024-04-24T17:17:58Z
dc.date.available2024-04-24T17:17:58Z
dc.date.issued2019
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Although its incidence has been increasing, colorectal cancer is rare in young patients. There are conflicting reports on its prognosis in young patients with colorectal cancers. The goal of this study is to investigate the prognostic factors in young patients with colorectal cancer. An observational, population-based, retrospective study. Materials and Methods: The clinicopathological characteristics, treatment approaches, and survival data of patients with colorectal cancers aged 30 years and younger were retrospectively analyzed. Results: A total of 32 patients were identified. Hematochezia and abdominal pain were the major signs of colorectal cancer. Left-sided tumors (rectum 53.1%, and left colon 25%) were found to be more common than right-sided (18.8%) and transverse colon tumors (3.1%). Curative surgery was performed in 81.3% of patients. Histologically, 43.8% of cancers found were poorly differentiated. According to the subtype, 21.9% were signet ring cell, and 25% were mucinous (colloid) tumors. Patients were evaluated as Stage III in 46.9% and Stage IV in 31.3% of cases. The 3-year progression-free survival (PFS) was 38.7%, and the 3-year overall survival (OS) was 53.2%. Stage IV disease and disease without curative surgery were poor prognostic factors, both for the OS and PFS. Conclusion: Prognosis was poor in young patients with colorectal cancer. In this institutional study, an advanced stage, left-sided localization, and poor histological feature were frequently detected. The stage and complete surgery were predictive factors for the long-term survival. In this respect, it is important for physicians to heighten their awareness of the increased incidence of colon cancer in younger patients.en_US
dc.identifier.doi10.14744/etd.2018.18109
dc.identifier.endpage68en_US
dc.identifier.issn2149-2247
dc.identifier.issn2149-2549
dc.identifier.issue1en_US
dc.identifier.startpage62en_US
dc.identifier.trdizinid319754
dc.identifier.urihttps://doi.org/10.14744/etd.2018.18109
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/319754
dc.identifier.urihttps://hdl.handle.net/11468/18487
dc.identifier.volume41en_US
dc.identifier.wosWOS:000462172800013
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherErciyes Univ Sch Medicineen_US
dc.relation.ispartofErciyes Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectColorectal Canceren_US
dc.subjectYoung Patientsen_US
dc.subjectDemographicsen_US
dc.subjectPrognosisen_US
dc.titleColorectal Cancer in Patients Aged ?30 Years: 17 Years of Experienceen_US
dc.titleColorectal Cancer in Patients Aged ?30 Years: 17 Years of Experience
dc.typeArticleen_US

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