Risk Factors for Extensively Drug-Resistant Acinetobacter baumannii in Neonatal Patients

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dc.contributor.authorTekin, Recep
dc.contributor.authorYolbas, Ilyas
dc.contributor.authorBozkurt, Fatma
dc.contributor.authorcevik, Saliha
dc.contributor.authorAlay, Handan
dc.contributor.authorozcan, Nida
dc.contributor.authorAktar, Fesih
dc.date.accessioned2024-04-24T16:24:09Z
dc.date.available2024-04-24T16:24:09Z
dc.date.issued2021
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction Extensively drug-resistant Acinetobacter baumannii infections (XDRABIs) are significant causes of mortality and morbidity in neonatal patients due to the treatment difficulties and limitations. In the present study, we aimed to evaluate the characteristics and risk factors for XDRABIs acquisition during hospitalization. Methods We investigated the risk factors of health care-associated infections (HCAIs) caused by multidrug-resistant A. baumannii in the four neonatal units between January 2008 and December 2018. The patients and the control group's data and culture results were recorded and analyzed on a daily basis. Results A total of 70 patients infected with XDRABIs and 118 control patients were included in the study. Univariate analysis showed that prematurity, gestation age, birth weight, mechanical ventilation, parenteral nutrition, transfusion, use of glycopeptides, and aminoglycosides were significantly associated with XDRABIs. In the univariate analysis, gestation age, mechanical ventilation, transfusion, parenteral nutrition, use of glycopeptides, carbapenems, and aminoglycosides were significantly associated with mortality. In the multiple logistic regression analysis, gestation age (p = 0.034), transfusion (p < 0.001), and use of glycopeptides (p = 0.019) were determined to be independent predictors of mortality in newborn infants with XDRABIs (Rsquare = 0.546). Conclusion Determination of the risk factors, avoiding invasive procedures, rational use of antibiotics will lead to a decrease in the mortality and morbidity rates related to XDRABIs.en_US
dc.identifier.doi10.1055/s-0040-1721446
dc.identifier.endpage35en_US
dc.identifier.issn1305-7707
dc.identifier.issn1305-7693
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85098234031
dc.identifier.scopusqualityQ4
dc.identifier.startpage31en_US
dc.identifier.urihttps://doi.org/10.1055/s-0040-1721446
dc.identifier.urihttps://hdl.handle.net/11468/16543
dc.identifier.volume16en_US
dc.identifier.wosWOS:000599186400002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofJournal of Pediatric Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcinetobacter Baumanniien_US
dc.subjectNeonatalen_US
dc.subjectRisk Factoren_US
dc.titleRisk Factors for Extensively Drug-Resistant Acinetobacter baumannii in Neonatal Patientsen_US
dc.titleRisk Factors for Extensively Drug-Resistant Acinetobacter baumannii in Neonatal Patients
dc.typeArticleen_US

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