Antimicrobial activity of the tar obtained from the roots and stems of Pinus brutia

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dc.contributor.authorKizil, M
dc.contributor.authorKizil, G
dc.contributor.authorYavuz, M
dc.contributor.authorAytekin, Ç
dc.date.accessioned2024-04-24T16:24:14Z
dc.date.available2024-04-24T16:24:14Z
dc.date.issued2002
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe antimicrobial activity of the crude and methanol, hexane, chloroform. petroleum ether, ethyl acetate and n-butanol extracts of tar obtained from the roots and stems of Pinus brutia Ten., used in the folk medicine of Turkey, were screened in vitro for antimicrobial activity against clinically isolated bacterial strains: Staphylococcus aureus ( 15 isolates), Streptococcus pyogenes ( 12 isolates), Escherichia coli (17 isolates) and the yeast fungus Candida albicans (3 isolates) by the paper disc diffusion method. Results revealed that a crude extract of the tar is highly effective against all tested microorganisms by preventing their growth to a significant extent. All the organic extracts showed similar moderate antimicrobial activity against tested microorganisms at a concentration of 80 mug/mL. The results demonstrate that the crude tar extract has a very broad spectrum of activity, and suggests that it may be useful in the treatment of various microbial infections, The results suggest that traditional folk medicine could be used a guide in our continuing search for new natural products with potential medicinal properties.en_US
dc.identifier.doi10.1076/phbi.40.2.135.5840
dc.identifier.endpage138en_US
dc.identifier.issn1388-0209
dc.identifier.issn1744-5116
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0036062450
dc.identifier.scopusqualityQ1
dc.identifier.startpage135en_US
dc.identifier.urihttps://doi.org/10.1076/phbi.40.2.135.5840
dc.identifier.urihttps://hdl.handle.net/11468/16595
dc.identifier.volume40en_US
dc.identifier.wosWOS:000175386000008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofPharmaceutical Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleAntimicrobial activity of the tar obtained from the roots and stems of Pinus brutiaen_US
dc.titleAntimicrobial activity of the tar obtained from the roots and stems of Pinus brutia
dc.typeArticleen_US

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