Evaluation of the Mean Platelet Volume in Children with Juvenile Idiopathic Arthritis

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dc.contributor.authorSen, Velat
dc.contributor.authorEce, Aydin
dc.contributor.authorUluca, Unal
dc.contributor.authorGunes, Ali
dc.contributor.authorTan, Ilhan
dc.contributor.authorTuncel, Tuba
dc.contributor.authorAktar, Fesih
dc.date.accessioned2024-04-24T17:18:02Z
dc.date.available2024-04-24T17:18:02Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractJuvenile idiopathic arthritis (JIA) is the most common chronic inflammatory arthritis in children. Mean platelet volume (MPV) is an indicator of platelet size and has been investigated as an inflammation marker in several diseases. This study was designed to investigate the MPV values in patients with JIA and healthy subjects, and determine the correlation between MPV, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR). The hospital records of a total of 40 children with JIA, diagnosed using the International League of Associations for Rheumatology (ILAR) criteria, and 40 healthy controls were enrolled into the study. White blood cell count (WBC), platelet count, CRP, ESR, and MPV levels were retrospectively recorded. Children with JIA had significantly higher MPV values (8.28 +/- 1.12 fL) compared to the control group (7.53 +/- 1.07 fL) (p=0.003). Significant correlations were found between MPV, ESR, and CRP in the JIA group (r=0.676, p<0.001 and r=0.430, p<0.006). In addition, a negative correlation was found between platelet count and MPV (r=-0.818, p<0.001) in JIA patients. There was no significant difference in WBC values between the patient and the control groups (p>0.05). Our results suggest that MPV levels may be a useful marker of inflammation and prognostic factor for atherosclerosis risk in pediatric JIA patients.en_US
dc.identifier.doi10.15197/sabad.1.11.83
dc.identifier.endpage267en_US
dc.identifier.issn1304-3889
dc.identifier.issn1304-3897
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84920503708
dc.identifier.scopusqualityN/A
dc.identifier.startpage262en_US
dc.identifier.urihttps://doi.org/10.15197/sabad.1.11.83
dc.identifier.urihttps://hdl.handle.net/11468/18559
dc.identifier.volume11en_US
dc.identifier.wosWOS:000421938200009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherModestum Ltden_US
dc.relation.ispartofEuropean Journal of General Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChildrenen_US
dc.subjectJuvenile Idiopathic Arthritisen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectInflammationen_US
dc.titleEvaluation of the Mean Platelet Volume in Children with Juvenile Idiopathic Arthritisen_US
dc.titleEvaluation of the Mean Platelet Volume in Children with Juvenile Idiopathic Arthritis
dc.typeArticleen_US

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