Multiple endocrine neoplasia type 2A syndrome (MEN2A) and usefulness of 68Ga-DOTATATE PET/CT in this syndrome

dc.contributor.authorTuzcu, Sadiye Altun
dc.contributor.authorPekkolay, Zafer
dc.date.accessioned2024-04-24T17:45:06Z
dc.date.available2024-04-24T17:45:06Z
dc.date.issued2019
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate a new imaging method 68Ga-DOTATATE PET/CT as an alternative method to diagnose evidence of neuroendocrine tumors or their metastasis (if any) in patient with MEN 2A. METHODS: Three patients( 2F, 1M; age 28,46 and 50 years) with MEN 2A syndrome who underwent 68Ga-DOTATATE PET/CT scan were prospectively evaluated. PET/CT images were analyzed with measurement of maximum standardized uptake value (SUVmax). RESULTS: All patients had adrenal masses with increased uptake of 68Ga-DOTATATE (first case adrenal mass SUVmax: 9,1, second case adrenal mass SUVmax: 32,4(right) 30,3 (left ) and third case SUVmax:12,4). All of the patients had medulla?), thyroid carcinoma with increased uptake - of 68Ga-DOTATATE (first case SUVmax: 3,3 second case SUVmax:7,7 and third case SUVmax: left thyroid nodule: 19,4, right thyroid nodule: 21,2). Third case has a parathyroid adenoma with SUVmax: 2,8. CONCLUSIONS: New imaging method 68Ga-DOTATATE PET/CT may be an alternative method to diagnose MEN 2A patients. 68Ga-DOTATATE PET/CT can give a great opportunity to detecting the multiple neoplasia like MEN 2A with only one session.en_US
dc.identifier.endpage503en_US
dc.identifier.issn0003-469X
dc.identifier.issn2239-253X
dc.identifier.issue6en_US
dc.identifier.pmid30837349en_US
dc.identifier.startpage497en_US
dc.identifier.urihttps://hdl.handle.net/11468/22424
dc.identifier.volume90en_US
dc.identifier.wosWOS:000502819700003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherEdizioni Luigi Pozzien_US
dc.relation.ispartofAnnali Italiani Di Chirurgiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMen 2a Syndromeen_US
dc.subject68ga-Dotatate Pet/Cten_US
dc.subjectNeuroendocrine Tumorsen_US
dc.titleMultiple endocrine neoplasia type 2A syndrome (MEN2A) and usefulness of 68Ga-DOTATATE PET/CT in this syndromeen_US
dc.typeArticleen_US

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