In vitro research to evaluate the antioxidant effects, inhibiting enzymes, methicillin-resistant Staphylococcus aureus strains of Terminalia catappa extracts

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dc.authorid0000-0002-6168-5707en_US
dc.authorid0000-0002-8036-4693en_US
dc.authorid0000-0001-6548-7823en_US
dc.authorid0000-0002-4090-7227en_US
dc.contributor.authorBouagnon, Julie José Rita
dc.contributor.authorKonan, Yannick
dc.contributor.authorKouadio Ibrahime, Sinan
dc.contributor.authorKonan, Fernique
dc.contributor.authorBolou, Gbouhoury Erick Kévin
dc.contributor.authorKoffi, Legue Riphin
dc.contributor.authorYeo, Dodehé
dc.contributor.authorN'Guessan, Jean David
dc.contributor.authorZengin, Gökhan
dc.contributor.authorDjaman, Allico Joseph
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorDosso, Mireille
dc.date.accessioned2024-04-17T08:09:07Z
dc.date.available2024-04-17T08:09:07Z
dc.date.issued2024en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractAim: Contribute to the well-being of the Ivorian population through scientific proof of the use of Terminalia cattapa leaves extracts in traditional medicine. Methodology: The antioxidative effect of aqueous, water-alcoholic, ethyl acetate and hexane derivatives of Terminalia catappa leaves was measured by six tests: DPPH (2-diphenyl-1-picrylhydrazyl), ABTS (2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)), FRAP (ferric ion reducing antioxidant power), PPBD (phosphomolybdenum), CUPRAC (cupric ion reducing antioxidant capacity) and MCA (metal chelating activity). The inhibition of the activity of five enzymes (acetylcholinesterase, butyrylcholinesterase, tyrosinase, amylase and glucosidase) was also determined. In addition, the broadcast method was used to evaluate impact of the samples on methicillin-resistant Staphylococcus aureus (MRSA) strains. Results: Highest antioxidant capacity was obtained in the ethanolic sample for DPPH, ABTS, FRAP and PPBD tests. Ethyl acetate sample produced the best CUPRAC and MCA tests. Among inhibitory effect of samples on the five enzymes, aqueous sample showed the strongest anti-acetylCholynesterase and anti-butyrylCholynesterase activity. Best anti-tyrosinase and anti-amylase activity were obtained with the ethanolic sample. Hexane sample obtained the best anti-glucosidase activity while ethanolic and aqueous samples obtained none. All extracts showed no activity on the MRSA strains tested. Conclusion: The chemical compounds present in Terminalia cattapa leaves extracts would not be responsible for the use made in traditional medicine against infections.en_US
dc.identifier.citationBouagnon, J. J. R., Konan, Y., Sinan, K. I., Konan, F., Bolou, G. E. K., Koffi, L. R. ve diğerleri. (2024). In vitro research to evaluate the antioxidant effects, inhibiting enzymes, methicillin-resistant Staphylococcus aureus strains of Terminalia catappa extracts. Scientific African, 23, 1-9.en_US
dc.identifier.doi10.1016/j.sciaf.2024.e02058
dc.identifier.endpage9en_US
dc.identifier.issn2468-2276
dc.identifier.scopus2-s2.0-85185171354
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S2468227624000024?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/11468/13897
dc.identifier.volume23en_US
dc.identifier.wosWOS:001178582000001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.institutionauthorDosso, Mireille
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofScientific African
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-infectious plantsen_US
dc.subjectAntimicrobial Resistance (AMR)en_US
dc.subjectCôte d'Ivoireen_US
dc.subjectTraditional medicineen_US
dc.titleIn vitro research to evaluate the antioxidant effects, inhibiting enzymes, methicillin-resistant Staphylococcus aureus strains of Terminalia catappa extractsen_US
dc.titleIn vitro research to evaluate the antioxidant effects, inhibiting enzymes, methicillin-resistant Staphylococcus aureus strains of Terminalia catappa extracts
dc.typeArticleen_US

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